Results 71 to 80 of about 359,641 (286)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Biological Assessments of Six Selected Fishes, Amphibians, and Mussels in Illinois [PDF]

, 1996
ID: 8758; issued November 1, 1996INHS Technical Report prepared for Illinois Department of Natural Resources, Division of Natural ...
Cummings, Kevin S., Page, Lawrence M., Phillips, Christopher A.   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Guiding principles for sustainable bamboo forest management planning Benishangul-Gumuz Regional State (BGRS) [PDF]

, 2019
Benishangul-Gumuz Regional State (BGRS) is the region of Ethiopia with the greatest bamboo forest cover. The resource has, however, encountered heavy degradation in recent years due to fires for farming and for hunting, mass flowering, unsustainable ...
Atmadja, Stibniati, Beyessa, Mengistu, Boissière, Manuel   +2 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

UniText: A Unified Framework for Chinese Text Detection, Recognition, and Restoration in Ancient Document and Inscription Images

Applied Sciences
Processing ancient text images presents significant challenges due to severe visual degradation, missing glyph structures, and various types of noise caused by aging.
Lu Shen, Zewei Wu, Xiaoyuan Huang, Boliang Zhang, Su-Kit Tang, Jorge Henriques, Silvia Mirri   +6 more
doaj   +1 more source

L. N. Parijskiy about the church situation in America in the 1940th [PDF]

Вестник Православного Свято-Тихоновского гуманитарного университета: Серия ИИ. История, история Русской Православной Церкви, 2012
The published document is the report of L.N. Parijskiy, the employee of the Moscow Patriarchate, about results of his visit to North America. The travel of the commission consisting of metropolitan Gregory (Tchukhov) and L.N. Parijskiy, occurred in 1947.
Kostriukov Andrei
doaj  

Inside the "Black Box" of River Restoration: Using Catchment History to Identify Disturbance and Response Mechanisms to Set Targets for Process-Based Restoration

Ecology and Society, 2010
Many river restoration projects fail. Inadequate project planning underpins many of the reasons given for failure (such as setting overly ambitious goals; selecting inappropriate sites and techniques; losing stakeholder motivation; and neglecting to ...
Sarah Mika, Joanna Hoyle, Garreth Kyle, Timothy Howell, Benjamin Wolfenden, Darren Ryder, Daniel Keating, Andrew Boulton, Gary Brierley, Andrew P. Brooks, Kirstie Fryirs, Michelle Leishman, Mark Sanders, Angela Arthington, Robert Creese, Mark Dahm, Craig Miller, Brad Pusey, Alexandra Spink   +18 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source