Results 91 to 100 of about 1,802,735 (277)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Sugarcane Cultivar CP 89-2143 Descriptive Fact Sheet
EDIS, 2018 The selection of a sugarcane cultivar that eventually becomes a production success is probably due in equal parts to the cultivar's attributes, word of mouth, gut feeling, and luck. This fact sheet provides many of the attributes cultivar identification
M.P. Singh, H.S. Sandhu, R.A. Gilbert
doaj +1 more source
Incomes in South Africa since the fall of Apartheid [PDF]
This paper examines changes in individual real incomes in South Africa between 1995 and 2000. We document substantial declines—on the order of 40%—in real incomes for both men and women.
James Levinsohn +2 more
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Termination as the Basis for Classification of Document Texts
Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2017 This article discusses the principles of classification of document texts from the point of view of records management and document linguistics; studies features of the terms of fixing the scope of the text (ambiguity, the presence of a strict definition,
Marina V. Kosova, Roza R. Sharipova
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Price Ratios and the Cross-section of Common Stock Returns on Bucharest Stock Exchange: Empirical Evidence [PDF]
This paper tests the relationship between above market returns and beta, size, leverage, book-to-market equity and earning-price ratios for the Bucharest Stock Exchange common stocks.
Tudor, Cristiana
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
El processament dels recursos electrònics
BiD: Textos Universitaris de Biblioteconomia i Documentació, 1998 Anàlisi d’alguns aspectes del paper de les biblioteques en l’entorn, parcialment electrònic, del moment actual. S’examina el concepte de col·lecció digital, la selecció i el control bibliogràfic dels recursos electrònics, i la normativa per controlar ...
Estivill Rius, Assumpció
doaj