Results 81 to 90 of about 6,834,762 (337)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

A Methodology for Database and Document Selection

open access: yesInt. J. Comput., 2011
As web users are facing the problems of information overload and drowning due to the significant and rapid growth in the amount of information and the number of users so there is need to provide Web users the more exactly needed information which is ...
R. Tiwari, M. Husain, Anil Agrawal
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

XML Reconstruction View Selection in XML Databases: Complexity Analysis and Approximation Scheme

open access: yes, 2010
Query evaluation in an XML database requires reconstructing XML subtrees rooted at nodes found by an XML query. Since XML subtree reconstruction can be expensive, one approach to improve query response time is to use reconstruction views - materialized ...
A. Balmin   +11 more
core   +1 more source

Naive Bayes Classification in The Question and Answering System [PDF]

open access: yes, 2013
—Question and answering (QA) system is a system to answer question based on collections of unstructured text or in the form of human language. In general, QA system consists of four stages, i.e.
Jeanny , Pragantha   +2 more
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Revistes electròniques, comunicació científica i biblioteques

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2001
El recent auge de les revistes científiques electròniques va tenir els seus inicis quan les biblioteques van començar a tenir accés a la World Wide Web (WWW) a mitjan dels noranta.
Keefer, Alice
doaj  

Evaluation of Fingerprint Selection Algorithms for Local Text Reuse Detection

open access: yesApplied Computer Systems, 2020
Detection of local text reuse is central to a variety of applications, including plagiarism detection, origin detection, and information flow analysis.
Jēkabsons Gints
doaj   +1 more source

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