Results 111 to 120 of about 1,889,843 (332)
Systematic ReviewsBackground This protocol outlines a scoping review with the objective of identifying and exploring planetary health considerations within existing health guidelines and health technology assessments (HTA).
Thomas Piggott +14 more
doaj +1 more source
Klinicist, 2019 The importance of the problem of myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA) increases yearly with accumulation of more statistical data.
A. S. Shilova +4 more
doaj +1 more source
Appendix B: IEEE Document‐Type Definitions (DTDs) [PDF]
, 2013 Denis L. Baggi, Goffredo Haus
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Проблеми Законності, 2015 Nowadays all over the world new protected areas are being created. In Ukraine this process is developed within European programs. During the years of independence many new protected areas were created.
Б. В. Даниленко
doaj +1 more source
Fostering SLA-Driven API Specifications [PDF]
, 2018 Software architecture tendencies are shifting to a microservice paradigm. In this context, RESTful APIs are being established the standard of integration. API designer often identifies two key issues to be competitive in such growing market.
Fernández Montes, Pablo +2 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
XML document design via GN-DTD [PDF]
, 2010 Designing a well-structured XML document is important for the sake of readability and maintainability. More importantly, this will avoid data redundancies and update anomalies when maintaining a large quantity of XML based documents.
Wang, Bing, Zainol, Zurinahni
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source