Results 41 to 50 of about 1,380,887 (296)

Consensus of Chinese Experts on the Diagnosis and Treatment of Type Ⅰ Interferonopathy

罕见病研究
Type Ⅰ interferonopathy is an autoinflammatory disease that affects multiple systems, with a high disability and mortality rate. It profoundly impacts the quality of life of patients and poses a considerable burden on their families and society.
Chinese Alliance of Pediatric Rheumatic & Immunologic Diseases, Chinese Pharmacists Association Rare Diseases Medication Working Committee   +1 more
doaj   +1 more source

Retrieving with good sense [PDF]

, 2000
Although always present in text, word sense ambiguity only recently became regarded as a problem to information retrieval which was potentially solvable.
Sanderson, M.
core   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

RTP/I Payload Type Definition for Feedback Tools [PDF]

, 2001
This document specifies an application-level protocol (i.e., payload type) for feedback tools using the Real Time Protocol for Distributed Interactive Media (RTP/I).
Vogel, Jürgen
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The interpretation of disease phenotypes to identify TSE strains in mice: characterisation of BSE using PrP^Sc distribution patterns in the brain

Veterinary Research, 2012
In individual animals affected by transmissible spongiform encephalopathies, different disease phenotypes can be identified which are attributed to different strains of the agent.
Corda Erica, Beck Katy E, Sallis Rosemary E, Vickery Christopher M, Denyer Margaret, Webb Paul R, Bellworthy Susan J, Spencer Yvonne I, Simmons Marion M, Spiropoulos John   +9 more
doaj   +1 more source

Systems biology markup language (SBML) level 3 package: multistate, multicomponent and multicompartment species, version 1, release 2

Journal of Integrative Bioinformatics, 2020
Rule-based modeling is an approach that permits constructing reaction networks based on the specification of rules for molecular interactions and transformations.
Zhang Fengkai, Smith Lucian P., Blinov Michael L., Faeder James, Hlavacek William S., Juan Tapia Jose, Keating Sarah M., Rodriguez Nicolas, Dräger Andreas, Harris Leonard A., Finney Andrew, Hu Bin, Hucka Michael, Meier-Schellersheim Martin   +13 more
doaj   +1 more source

RTP/I Payload Type Definition for Application Launch Tools [PDF]

, 2001
This document specifies an application-level protocol (i.e., payload type) for application launch tools using the Real-Time Protocol for Distributed Interactive Media (RTP/I).
Vogel, Jürgen
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source