Results 71 to 80 of about 1,889,843 (332)

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker   +7 more
wiley   +1 more source

Two-Stage Document Length Normalization for Information Retrieval

open access: yes, 2015
The standard approach for term frequency normalization is based only on the document length. However, it does not distinguish the verbosity from the scope, these being the two main factors determining the document length.
Na, Seung-Hoon
core   +1 more source

Expressing advanced user preferences in component installation [PDF]

open access: yes, 2009
State of the art component-based software collections - such as FOSS distributions - are made of up to dozens of thousands components, with complex inter-dependencies and conflicts.
Treinen, Ralf, Zacchiroli, Stefano
core   +5 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Academic integrity and contract cheating policy analysis of colleges in Ontario, Canada

open access: yesInternational Journal for Educational Integrity, 2019
In this study, we analyzed the academic integrity policies of colleges in Ontario, Canada, casting a specific lens on contract cheating. We extracted data from 28 individual documents from 22-publicly-funded colleges including policies and procedures (n =
Brenda M. Stoesz   +3 more
doaj   +1 more source

Exploration of species diversity and vegetation pattern in temperate conifer forests along altitudinal gradients in the Western Himalayas

open access: yesFrontiers in Forests and Global Change, 2023
The moist temperate forests extend along the whole length of outer ranges of Himalaya between the subtropical pine forests and sub-alpine timberline formation with a rainfall from 400 mm to 800 mm. The altitudinal range is from 1500 m to 3000 m.
Muhammad Hashim   +10 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Climate Change and Human Migration: Towards More Humane Interpretation of Refugee

open access: yesUdayana Journal of Law and Culture, 2018
This article seeks to highlight the existing 1951 Convention relating to the Status of Refugees (hereinafter referred to as Refugee Convention) and the possibilities of the document to encompass climate-induced migration by modifying, reconstructing and ...
I Gede Eka Sarjana
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Systems biology markup language (SBML) level 3 package: multistate, multicomponent and multicompartment species, version 1, release 2

open access: yesJournal of Integrative Bioinformatics, 2020
Rule-based modeling is an approach that permits constructing reaction networks based on the specification of rules for molecular interactions and transformations.
Zhang Fengkai   +13 more
doaj   +1 more source

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