Results 271 to 280 of about 16,255,401 (402)

History of clinical trials for the treatment of tuberculosis in China. Part 1: early 'translational' work and observational and non-randomised studies. [PDF]

J R Soc Med
Yu X, Chen Y, Podolsky SH.
europepmc   +1 more source

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu, Wentao Chen, Yahong Wu, Zhen Guo, Jun Chen, Chen Tian, Pan Wang, Shaopeng Zeng, Bin Xu, Jing Duan, Shilong Han, Xiao Xiong, Jing Zhang   +12 more
wiley   +1 more source

A Transformer-Based Pipeline for German Clinical Document De-Identification. [PDF]

Appl Clin Inform
Arzideh K, Baldini G, Winnekens P, Friedrich CM, Nensa F, Idrissi-Yaghir A, Hosch R.   +6 more
europepmc   +1 more source

Myostatin Levels in SMA Following Disease‐Modifying Treatments: A Multi‐Center Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study investigated myostatin levels in SMA patients receiving disease‐modifying therapies (DMTs) to understand their relationship with treatment duration and functional status. Methods Our study includes both cross‐sectional and longitudinal analyses of myostatin levels in treated SMA patients.
Fiorella Piemonte, Sara Petrillo, Anna Capasso, Giorgia Coratti, Adele D'Amico, Michela Catteruccia, Maria Carmela Pera, Concetta Palermo, Marika Pane, Emanuela Abiusi, Gianpaolo Cicala, Marianna Villa, Chiara Bravetti, Chiara Arpaia, Agnese Novelli, Salvatore Falqui, Stefania Fiori, Giulia Napoli, Silvia Baroni, Francesco Danilo Tiziano, Enrico Bertini, Giacomo Comi, Stefania Corti, Eugenio Mercuri   +23 more
wiley   +1 more source

Converting Health Level 7 Clinical Document Architecture (CDA) documents to Observational Medical Outcomes Partnership Common Data Model (OMOP CDM) by leveraging CDA Template definitions. [PDF]

JAMIA Open
Katsch F, Hussein R, Stamm T, Duftschmid G.   +3 more
europepmc   +1 more source

Nuclei‐Specific Amygdala Enlargement Is Linked to Psychiatric Comorbidities in Drug‐Resistant Focal Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amygdala enlargement has been the subject of controversial studies regarding its significance in terms of pathogenicity both in epilepsy and in psychiatric comorbidities such as anxiety, depression, and post‐traumatic stress disorder.
Hélène Mourre, Julia Makhalova, Lisa Soncin, Elodie Garnier, Hugo Dary, Arnaud Le Troter, Roy A. M. Haast, Benoit Testud, Marie Arthuis, Samuel Medina Villalon, Stanislas Lagarde, Francesca Pizzo, Christian Bénar, Jean‐Philippe Ranjeva, Maxime Guye, Fabrice Bartolomei   +15 more
wiley   +1 more source

Careful design of Large Language Model pipelines enables expert-level retrieval of evidence-based information from syntheses and databases. [PDF]

PLoS One
Iyer R, Christie AP, Madhavapeddy A, Reynolds S, Sutherland W, Jaffer S.   +5 more
europepmc   +1 more source

The Impact of Diabetes and Metabolic Syndrome Burden on Pain, Neuropathy Severity and Fiber Type

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Determine the association between diabetes and metabolic syndrome (MetS) burden (number of MetS criteria fulfilled) and pain, neuropathy severity, and fiber type involvement in individuals with established polyneuropathy. Methods The Peripheral Neuropathy Research Registry was queried for individuals with type 1 and type 2 diabetes ...
Long Davalos, Brian C. Callaghan, Lavanya Muthukumar, Simone Thomas, Evan L. Reynolds, A. Gordon Smith, J. Robinson Singleton, Ahmet Höke, Senda Ajroud‐Driss, Mazen M. Dimachkie, Stefanie Geisler, David M. Simpson, PNRR Study Group, Amro M. Stino   +13 more
wiley   +1 more source

Enhanced effective convolutional attention network with squeeze-and-excitation inception module for multi-label clinical document classification. [PDF]

Sci Rep
Venkata Krishna Reddy M, Raghavendar Raju L, Sai Prasad K, Kumari DDA, Veerabhadram V, Yamsani N.   +5 more
europepmc   +1 more source

Precision‐Optimised Post‐Stroke Prognoses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Current medicine cannot confidently predict who will recover from post‐stroke impairments. Researchers have sought to bridge this gap by treating the post‐stroke prognostic problem as a machine learning problem, reporting prediction error metrics across samples of patients whose outcomes are known.
Thomas M. H. Hope, Howard Bowman, Rachel M. Bruce, Alex P. Leff, Cathy J. Price   +4 more
wiley   +1 more source