Results 71 to 80 of about 2,583,085 (297)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A Falsification View of Success Typing
Dynamic languages are praised for their flexibility and expressiveness, but static analysis often yields many false positives and verification is cumbersome for lack of structure.
Jakob, Robert, Thiemann, Peter
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Duplicate Detection in the Reuters Collection [PDF]
While conducting some experiments with the Reuters collection, it was discovered that contained within it were a number of documents that were exact duplicates of each other (see Figure 1).
Sanderson, M.
core +1 more source
Assembling and enriching digital library collections [PDF]
People who create digital libraries need to gather together the raw material, add metadata as necessary, and design and build new collections. This paper sets out the requirements for these tasks and describes a new tool that supports them interactively,
Bainbridge, David +2 more
core +2 more sources
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Ilex crenata 'Helleri' Helleri Holly
This document provides an overview of the dwarf Japanese holly (Ilex crenata ‘Helleri’), highlighting its characteristics, uses, and cultivation requirements.
Edward Gilman
doaj +1 more source
Evaluation of an Internet Document Delivery Service [PDF]
An Internet-based Document Delivery Service (DDS) has been developed within the framework of the CNR ( the Italian Research National Council) Project BiblioMIME, in order to take advantage of new Internet technologies and promote cooperation among ...
Abba, Laura +4 more
core
An evaluation of Bradfordizing effects [PDF]
The purpose of this paper is to apply and evaluate the bibliometric method Bradfordizing for information retrieval (IR) experiments. Bradfordizing is used for generating core document sets for subject-specific questions and to reorder result sets from ...
Bates Marcia J. +23 more
core +8 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source

