Results 21 to 30 of about 51,461 (259)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Principal directions for deploying secure document workflow on artificial intelligence platforms
Theory and Practice of Public AdministrationThe article explores the principal directions for deploying secure document workflow on artificial intelligence platforms using local large language models (LLMs). It analyzes the technological features and functional capabilities of tools such as Ollama
Alexander Orlov +2 more
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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MANAGING HUMAN FACTORS IN IMPLEMENTING ELECTRONIC DOCUMENT SYSTEM IN THE PUBLIC SECTOR [PDF]
Challenges of the Knowledge Society, 2012 Document management underlies the activities of almost every organization. Correctly managed correspondence and organized document circulation characterize successful performance particularly in the public sector organizations.
TOMS LEIKUMS
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Customizable document control solution for 3D printing at the point-of-care
3D Printing in Medicine, 2023 Background The rapid expansion and anticipated U.S Food and Drug Administration regulation of 3D printing at the point-of-care necessitates the creation of robust quality management systems.
Maxwell Lohss +2 more
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Design of Generalized Search Interfaces for Health Informatics
Information, 2021 In this paper, we investigate ontology-supported interfaces for health informatics search tasks involving large document sets. We begin by providing background on health informatics, machine learning, and ontologies.
Jonathan Demelo, Kamran Sedig
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
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Using Electronic Systems for Document Management in Economic Entities [PDF]
Informatică economică, 2007 Document workflow and management, be them scanned documents, computer-generated e-documents or complex file formats, are critical elements for the success of an organization.
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Journal of Pathology Informatics, 2012 Background: For decades anatomic pathology (AP) workflow have been a highly manual process based on the use of an optical microscope and glass slides.
Jonhan Ho, Orly Aridor, Anil V Parwani
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