Results 41 to 50 of about 2,439 (288)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Estructura del Sistema de Gestión Integral de Documentos de archivo [SiGeID 1.0]

open access: yesRevista Interamericana de Bibliotecología, 2012
The new context imposes on organizations the vital necessity of having appropriate communication infrastructures that allow them to get actual and enough knowledge about their environment.
Dominica Legañoa Ferrá   +5 more
doaj  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Conceptos e indicadores de calidad en la actividad archivística

open access: yesRevista Habanera de Ciencias Médicas, 2015
Introducción: Los archivos son importantes áreas de apoyo, donde una mayor eficacia y eficiencia en la prestación del servicio de gestión documental puede reportar beneficios al desempeño general de las instituciones hospitalarias. Objetivo: Analizar los
Rosa Mayelin Guerra Bretaña   +2 more
doaj  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Evaluation Model for developing effective indicators for health surveillance actions in Brazil

open access: yesRevista Brasileira de Saúde Materno Infantil
Objective: to present an evaluation model for developing effective indicators for the Vigilância Sanitária (VISA) (Sanitary and Health Surveillance) actions in Brazil. Methods: an exploratory, evaluative study from primary sources data - electronic form
Eronildo Felisberto   +8 more
doaj   +1 more source

An integrated document management system

open access: yes, 1990
We propose an approach towards an integrated document processing and management system that has the intention to capture essentially freely structured documents, like those typically used in the office domain. The ANASTASIL component is capable to reveal the structure as well as the contents of complex office documents.
Dengel, Andreas   +2 more
openaire   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Propuesta de un sistema de información documental para las televisiones locales

open access: yesAnales de Documentación, 2005
Se lleva a cabo una propuesta de organización de la información documental en las televisiones locales en el marco de la teoría sistémica de la información, tomando como referencia el concepto de Information Management System como método de organizar la ...
Jorge Caldera Serrano   +1 more
doaj  

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