Results 41 to 50 of about 77,722 (334)

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

URBAN PLANNING, AGENTS AND REPRESENTATIONS: CREATION OF THE BANHADO, SÃO JOSÉ DOS CAMPOS LANDMARK [PDF]

Ambiente & Sociedade, 2017
This historical and sociological research explores urban planning as a symbolic system. By means of a case study, and the use of documental analysis, it asses the symbolic capital contained in urban planning propositions developed for the Banhado, an ...
DOUGLAS ALMEIDA SILVA, PAULA VILHENA CARNEVALE VIANNA, VALÉRIA REGINA ZANETTI   +2 more
doaj   +3 more sources

Linking forest cover, soil erosion and mire hydrology to late-Holocene human activity and climate in NW Spain [PDF]

, 2014
This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further ...
Aira Rodríguez MJ, Benito E, Carrión Y, Cheburkin AK, Clymo RS, Costa Casais M, FAO, Fægri K, García Salinas F, Goeury C, Grimm EC, Grimm EC, Innes JB, Martínez Cortizas A, Rochette Cordeiro AM, Siiriäinen A, Smith AG, Starkel L, Taboada Castro MT, Taboada Castro MT, Van Andel TH, Van Geel B, Van Geel B, Vánky K   +23 more
core   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Managing the evolution of a urban system. The UNESCO site of Crespi d’Adda

Techne, 2016
The workers’ village of Crespi d’Adda, registered in the UNESCO World Heritage List in 1995, consists of a large industrial complex of approximately 90,000 square metres, abandoned in 2004 and made up of around a hundred residential buildings which were ...
Maria Paola Borgarino, Paolo Gasparoli, Anna Teresa Ronchi, Matteo Scaltritti   +3 more
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Aqüífero Guarani: gestão compartilhada e soberania

Estudos Avançados, 2008
Este trabalho analisa a situação institucional do Mercosul em relação à gestão compartilhada dos recursos hídricos a partir do Sistema Aqüífero Guarani, importante reservatório de águas subterrâneas que ocorre no território da Argentina, do Brasil ...
Wagner Costa Ribeiro
doaj   +1 more source

D7.6 Data Management System and documentation

, 2021
This report presents the main components and functionalities of the Data Management System (DMS) implemented by ARICE. The strategic targets driving this development have been: (i) the need to simplify the original plan to address challenges arising from changes in involved partners during the project; (ii) the need, in a legacy perspective, to adopt ...
Vito Vitale, Giulio Verazzo, Mauro Mazzola   +2 more
openaire   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source