Results 121 to 130 of about 2,974,657 (301)

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen   +18 more
wiley   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

open access: yesAdvanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan   +24 more
wiley   +1 more source

Cuerpos marcados: la imagen como documento, testimonio y crítica social

open access: yesLa Trama de la Comunicación, 2015
[es] El presente trabajo busca reflexionar sobre los procesos de significación de un determinado uso de la fotografía documental, sobre cómo la imagen fotográfica se emplea no sólo para construir documentación sino también como imagen testimonial y ...
Leticia Rigat
doaj  

FOTOGRAFÍA DOCUMENTAL Y ANTROPOLÓGICA EN LA ENCRUCIJADA DEL SIGLO XXI

open access: yes, 2021
The history of photography is often presented in an artificial and reductionist way in a dichotomousway between artistic photography and documentary photography.
Muñoz-Jiménez, José Muñoz-Jiménez
core  

An Implantable Optogenetics‐Engineered Hydrogel for Amelioration of Rheumatoid Arthritis through Light‐Controlled Metabolic Reprogramming of Synovial Macrophages

open access: yesAdvanced Science, EarlyView.
An implantable hydrogel is designed to enable in situ and on‐demand secretion of GLP‐1 in synovium through blue light irradiation to activate GLP‐1R/HK2/VDAC1 pathway for upregulating tricarboxylic acid cycle and oxidative phosphorylation in macrophage, facilitating tissue repair and bone erosion recovery.
Dahai Hu   +10 more
wiley   +1 more source

La desactivación de la función crítica en la imagen documental

open access: yesAzafea: Revista de Filosofía, 2009
RESUMEN: Las experiencias en torno al uso de fotografías en el arte conceptual dan lugar a una crítica del papel del documento como testimonio de realidad y de sus connotaciones en el contexto de circulación de las imágenes.
Víctor del RÍO
doaj  

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

open access: yesAdvanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li   +6 more
wiley   +1 more source

The reception of artwork through photography

open access: yes, 2017
Relatório de Estágio do Mestrado em Estudos Curatoriais apresentado ao Colégio das ArtesThe aim of this dissertation is to focus on the analysis of the documentation and diffusion process of artwork through photography, giving importance to a type of ...
Garcia, Vítor José Ramos
core  

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

open access: yesAdvanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon   +20 more
wiley   +1 more source

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