Results 131 to 140 of about 2,974,657 (301)

Éticas y estéticas de la posmemoria en el audiovisual contemporáneo

open access: yesHistoria Actual On-Line, 2015
Si bien el concepto de la posmemoria se fragua a partir de las reflexiones derivadas en torno a la representación y transmisión del Holocausto, es cierto que en los últimos años dicho término también ha sido utilizado para designar un conjunto de ...
Laia Quílez Esteve
doaj  

Inhibition of Focal Adhesion Restricts Chemoresistance in Pancreatic Cancer by Targeting SLC7A11 Mediated Ferroptosis

open access: yesAdvanced Science, EarlyView.
FAK signaling drives chemoresistance and tumor evolution in pancreatic ductal adenocarcinoma. The FAK inhibitor IN10018 restores gemcitabine sensitivity by inducing SLC7A11‐mediated ferroptosis through the PI3K‐Akt pathway and remodeling the tumor microenvironment, reducing mesenchymal components while enhancing CD8+ T‐cell infiltration in preclinical ...
Yingjin Wang   +11 more
wiley   +1 more source

Uso de las técnicas de la fotografía documental y periodística como registro de la inclusión de los inmigrantes en Cuenca [PDF]

open access: yes, 2016
El presente trabajo de titulación es un proyecto fotográfico denominado “Uso de las técnicas de la fotografía documental y periodística como registro de la inclusión de los Inmigrantes en Cuenca”.
Campoverde Fernández, Paúl Alberto
core  

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

open access: yesAdvanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan   +11 more
wiley   +1 more source

Controlling Photochromism of Donor‐Acceptor Stenhouse Adducts on Micro‐Dot Arrays Beyond Human‐Eyes Resolution for Dynamic Light Encryption

open access: yesAdvanced Science, EarlyView.
This study presents a micro‐dot array strategy for dynamic light encryption, utilizing DASA‐based photochromism with resolution beyond human‐eye capacity. By precisely controlling isomerization kinetics, the method reveals multi‐layered encrypted information under specific light irradiation, enhancing information security and anti‐counterfeiting ...
Hongtao Hu   +10 more
wiley   +1 more source

En línea : IdeAs n° 13 - 2019 : Fotografía documental contemporánea en las Américas

open access: yes, 2019
N° coordonné par Marion Gautreau et Jean Kempf, en collaboration avec le comité de rédaction. Rédactrice en chef : Isabelle VagnouxSecrétariat de rédaction : Laura Martín Agudelo.
REGARDS (CJ)
core  

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

open access: yesAdvanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai   +8 more
wiley   +1 more source

Producción de foto-documental: gastronomía típica en la parroquia San Joaquín [PDF]

open access: yes, 2015
En este trabajo trataremos el tema de la gastronomía autóctona de la parroquia San Joaquín, como se elaboran los platos que la identifican y su aporte nutricional, además trataremos temas técnicos como lo son la elaboración de un foto-documental y la ...
Vanegas Cárdenas, Estefanía Carolina   +1 more
core  

A Novel Approach Based on Acceptor–Donor–Acceptor Type Molecules Enhances the Therapeutic Efficacy and Safety of Photothermal Therapy for Osteosarcoma

open access: yesAdvanced Science, EarlyView.
Jin et al. developed IEICO‐F nanoparticles with enhanced photothermal conversion efficiency via optimized push‐pull effect. Under 808 nm laser, these nanoparticles effectively generated heat to kill osteosarcoma cells and exhibited significant tumor suppression in vivo. Therefore, this novel A‐D‐A type molecule‐based photothermal therapy strategy holds
Zhijian Jin   +9 more
wiley   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma   +12 more
wiley   +1 more source

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