Results 131 to 140 of about 11,968 (260)

El hombre que no cesa: August Sander y Richard Avedon, artistas con cámaras fotográficas [PDF]

open access: yes, 2005
Actas de las Terceras Jornadas Imagen, Cultura y Tecnología celebradas del 28 al 30 de julio de 2004 en la Universidad Carlos III de ...
Portillo Guzmán, Fernando
core   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

open access: yesAdvanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang   +14 more
wiley   +1 more source

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

open access: yesAdvanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li   +9 more
wiley   +1 more source

La ontología de la imagen en la diáspora contemporánea de las pesquerías gallegas [PDF]

open access: yes, 2008
En el siguiente artículo presentamos una colección de fotografías etnográficas que dan a conocer la diáspora acontecida a mediados del siglo XX, de una parte de la flota pesquera gallega al Atlántico Sur y su asentamiento en el puerto gaditano.
Broullón Acuña, Esmeralda
core  

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu   +9 more
wiley   +1 more source

Exceptionally high mortality rate of the 1918 influenza pandemic in the Brazilian naval fleet. [PDF]

open access: yesInfluenza Other Respir Viruses, 2013
Schuck-Paim C   +3 more
europepmc   +1 more source

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

open access: yesAdvanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi   +16 more
wiley   +1 more source

From sea monsters to charismatic megafauna: Changes in perception and use of large marine animals. [PDF]

open access: yesPLoS One, 2019
Mazzoldi C   +12 more
europepmc   +1 more source

Arrangement and Timing: Photography, Causation and Anti-Empiricist Aesthetics [PDF]

open access: yes
According to the causal theory of photography (CTP), photographs acquire their depictive content from the world, whereas handmade pictures acquire their depictive content from their makers’ intentional states about the world. CTP suffers from what I call
Cavedon-Taylor, Dan
core  

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

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