Results 51 to 60 of about 207,894 (266)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

A federated search engine providing access to validated and organized "web" information within the World Agricultures Observatory [PDF]

open access: yes, 2010
Dans le cadre de l'initiative internationale " Observatoire des Agricultures du Monde (OAM) ", le Cirad s'est donné comme objectif la constitution d'un espace de production et d'accumulation de connaissances originales, en vue d'échanges, de réflexions ...
Bona, Audrey   +3 more
core  

Data fluidity in DARIAH -- pushing the agenda forward [PDF]

open access: yes, 2016
This paper provides both an update concerning the setting up of the European DARIAH infrastructure and a series of strong action lines related to the development of a data centred strategy for the humanities in the coming years.
Baillot, Anne   +2 more
core   +6 more sources

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Percepciones de la alta gerencia y modelo de gestión por competencias en empresas de Bogotá

open access: yesSuma de Negocios, 2013
This article discusses the perceptions and competence management model from top management in companies of Bogotá. The paper includes two experiences, developed in the framework of the professional specialization in Human Resources Management at Konrad ...
Marleny Cardona Acevedo   +2 more
doaj  

The Art & Science of Creating Effective Youth Programs [PDF]

open access: yes, 2017
"The Art & Science of Creating Effective Youth Programs" utilizes findings from a national collective impact study conducted by Algorhythm through their Youth Development Impact Learning System (YDiLS), which surveyed 27 organizations, 80 programs and ...
Kim Sabo-Flores, Peter York
core  

ERP customization failure: Institutionalized accounting practices, power relations and market forces [PDF]

open access: yes, 2007
Purpose: This paper examines a detailed case study of Enterprise Resource Planning (ERP) customization failure in an Egyptian state-owned company (AML) by drawing on new institutional sociology and its extensions.
Abdel-Kader, MG, Kholeif, A, Sherer, M
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Traditional and contemporary management accounting practices: A literature review

open access: yesRAN, 2019
The objective of this paper is to identify the traditional and contemporary management accounting practices used in various research articles as a basis to carry out studies on current cost practices, comparing and contrasting expert criteria.
Mónica Hernández-Madrigal
doaj  

Accounting for the recognition of information as an asset [PDF]

open access: yes, 2011
Tangible assets as property, plant and equipment continue to be important factors in the production of both goods and services. However, their relative importance has decreased through time as the importance of intangible, knowledge-based assets has ...
Abdel-Kader, M, El Tawy, NAH
core  

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