Results 71 to 80 of about 21,168,226 (244)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

UNIVERSIDADES-FUNDAÇÃO: A EMPRESARIALIZAÇÃO DA EDUCAÇÃO SUPERIOR EM PORTUGAL

open access: yesRevista Gestão Universitária na América Latina, 2014
This article deals with public management model of higher education to find out if there are advances in the process and structure of Portuguese universities transformed into a foundation when compared with the management of traditional higher education.
Joaquim Filipe Ferraz Esteves de Araújo   +2 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

HBIM Implementation in Architectural Heritage: A Multitemporal Case Study of the Church of La Sang in Llíria

open access: yesHeritage
The conservation of architectural heritage poses significant challenges in buildings characterised by complex construction sequences, cumulative transformations and fragmented documentation, where traditional methods are insufficient to coherently ...
Inmaculada Oliver-Faubel   +3 more
doaj   +1 more source

CREDENCIAMENTO PARA A OFERTA DE EAD COMO FATOR GERADOR DE INOVAÇÃO E MUDANÇA NO PROCESSO DE GESTÃO UNIVERSITÁRIA: UM ESTUDO DE CASO

open access: yesRevista Gestão Universitária na América Latina, 2018
Managing the modality of Distance Education (DE) in a Higher Education Institution (HEI) requires planning, reorganization and paradigm shift regarding the actions used in the face to face education. These are some factors that can lead to innovation and
Manoela Pierina Tagliaferro   +1 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

GESTÃO PÚBLICA DA UFPI: UMA ANÁLISE DO SEU PLANO DE DESENVOLVIMENTO INSTITUCIONAL (PDI)

open access: yesRevista Gestão Universitária na América Latina, 2012
This article was developed in order to collect data regarding the management models that stood out throughout the years and understand the importance of strategic planning for public institutions. Another goal was to identify the management model adopted
Adalgisa Costa Melo   +3 more
doaj  

Brazil and Spain: Management of Public Sports Policies [PDF]

open access: yesRevista Intercontinental de Gestão Desportiva, 2020
The study seeks to compare the sport management model in Brazil with that in Spain. For this, a bibliographic review and a documentary study were carried out.
Cintia Csucsuly Rocha   +2 more
doaj  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Documentary film riddles of globalization Proceedings

open access: yes, 2002
Available from Latvian Academic Library / LAL - Latvian Academic LibrarySIGLENational Film Centre of Latvia, Riga (Latvia); Culture Capital Foundation, Riga (Latvia); Soros Foundation - Latvia, Riga (Latvia); Baltic Media Centre, Svaneke (Denmark ...
European Documentary Network, Copenhagen (Denmark)   +4 more
core  

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