Results 81 to 90 of about 11,371 (266)
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
BBC producer choice and the management of organisational change
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Producer Choice was the title given to the trading system, designed around an internal market, which was introduced at the BBC in the years between 1991 and
Wegg-Prosser, Victoria, Wegg-Prosser, V.
core
Developing an entrepreneurial project management model for social enterprise organisations
Project management has emerged as a theoretical construct in guiding managerial decision-making, whilst transforming from its traditional dominance in the fields of construction and engineering into sectors such as social enterprise organisations.
James Mbiru (14743630)
core +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
GESTÃO PÚBLICA DA UFPI: UMA ANÁLISE DO SEU PLANO DE DESENVOLVIMENTO INSTITUCIONAL (PDI)
This article was developed in order to collect data regarding the management models that stood out throughout the years and understand the importance of strategic planning for public institutions. Another goal was to identify the management model adopted
Adalgisa Costa Melo +3 more
doaj
Brazil and Spain: Management of Public Sports Policies [PDF]
The study seeks to compare the sport management model in Brazil with that in Spain. For this, a bibliographic review and a documentary study were carried out.
Cintia Csucsuly Rocha +2 more
doaj
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Instructional design: Integration of the Q10 platform into the ADDIE model
Instructional design is intended to create effective and efficient experiences within education, adapting to the growing demands of the digital society and accelerated virtualization, a product of the COVID-19 pandemic.
Carlos Alcides Almidón Ortiz +3 more
doaj +1 more source
Collective farming in Nepal (Nepal agriculture collectives)
Between 2015 and 2019, a set of farmer collectives were piloted in DSI4MTF and served as a model for a novel approach to addressing the challenges of small and fragmented holdings in the Eastern Gangetic Plains, unequal landlord-tenant relations, and ...
International Water Management Institute
core
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source

