Results 81 to 90 of about 21,168,226 (244)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Organizational happiness, emotional intelligence, and a basic model of strategic management

Revista Gestión I+D, 2021
Organizational happiness, emotional intelligence, and strategic administration are fundamental in any current institution, regardless of its complexity.
María Victoria Velásquez
doaj  

Developing a strategic cost management model : combininig the balanced scorecard and activity-based costing in the context of diabetes education [PDF]

, 2006
viii, 93 leaves : ill. ; 29 cm.The study presents the development of a strategic cost management model that combines activity-based costing (ABC) with principles of the balanced scorecard (BSC).
Venkatramanan, Atulya, University of Lethbridge. Faculty of Management   +1 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Instructional design: Integration of the Q10 platform into the ADDIE model

Revista de Ciencias Sociales
Instructional design is intended to create effective and efficient experiences within education, adapting to the growing demands of the digital society and accelerated virtualization, a product of the COVID-19 pandemic.
Carlos Alcides Almidón Ortiz, Edith Miriam Coronado Pérez de Almidón, Mario Jesús Ormachea Mejía, Elescano Angel Almidón   +3 more
doaj   +1 more source

Analysis of construction projects stakeholders from corporate social responsibility

Cuadernos de Administración, 2017
The aim of the article is to present the Stakeholders’ analysis of housing construction projects from a corporate social responsibility approach and based on the application of the Stakeholder Circle methodology, complemented with some matrixes related ...
Mario Enrique Uribe Macías
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Turismo e geoconservação: uma análise do modelo de gestão do uso público no Parque Estadual de Vila Velha, Paraná

PASOS Revista de Turismo y Patrimonio Cultural, 2017
Located in Campos Gerais of Parana, southern Brasil, the Parque Estadual de Vila Velha (PEVV) is a conservation unit of great importance for its biotic and abiotic characteristics, recognized mainly by its geological formations of ...
Pedro G. Gonzáles Mantilla, Marcos Aurelio Tarlombani da Silveira, Margarete Araujo Teles   +2 more
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source