Results 51 to 60 of about 11,371 (266)
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Invest to Save: Report and Recommendations of the NSF-DELOS Working Group on Digital Archiving and Preservation [PDF]
Digital archiving and preservation are important areas for research and development, but there is no agreed upon set of priorities or coherent plan for research in this area.
Hedstrom, M. +9 more
core
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
The Work Programme: a new public governance policy or a continuation of new public management? [PDF]
Since the 1970s, the governance of labour market policies in the UK has been characterised by New Public Management (NPM) traits and since the late 1990s the welfare system has experienced a trend towards activation.
Fuertes, Vanesa, McQuaid, Ronald
core
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha +4 more
wiley +1 more source
This paper describes a human management model as conceived in organizations that carry out a strategic direction of staff, based on a critical look of traditional management and some of its notions, such as the classical perspective of strategic ...
Héctor Bermúdez Restrepo
doaj
Using documentary analysis to reveal narratives of mothering
This paper will outline a piece of research that did not aim primarily to use a narrative approach or to rely upon narrative inquiry. The initial focus of the research was concerned with using documentary analysis in order to investigate whether or ...
Kelly, Nancy
core
Development of a risk management model for public-private partnerships in Uganda
Thesis (PhD)--Stellenbosch University, 2023.ENGLISH SUMMARY: Governments are collaborating with the private sector through public-private partnerships (PPPs) to address the public infrastructure funding gaps and inefficiencies associated with ...
Bagenda, Bonny
core
Reconciliation responses, blame and expressions of guilt or shame [PDF]
Recipients of intergroup apologies have been found to prefer expressions of shame over guilt. However, there is little research comparing the responses of a wronged group with those of a blamed group.
Giner-Sorolla, Roger +5 more
core +1 more source

