Results 51 to 60 of about 373,604 (293)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Making history: post-historical commemorations of the past in British television [PDF]

open access: yes, 2007
The postmodernist re-evaluation of historical study has let to an awareness of the value of the moving image to the historian. Film can present us with glimpses of a past independent of discourse and its unique link with reality carries with it ...
Smith, L.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Thoroughly modern Mannheim and the postmodern Weltanschauung. [PDF]

open access: yes, 1997
There are a number of features of Mannheim’s method for the interpretation of weltanschauung that laid the foundations for his later sociology of knowledge and that could be considered as prefiguring the methodological principles of a postmodern world ...
Dant, Tim
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Externalizing Tacit Knowledge in Independent Documentary Film Production via Pattern Language [PDF]

open access: yesJournal of Library and Information Studies, 2008
Recently, Taiwan locally made documentary has been received high regards at international movie festivals and by domestic reviewers. The independent documentary producers in Taiwan are different from the commercial documentary producers in other ...
Ming-Shu Yuan
doaj   +1 more source

AMISH TEENAGERS VIEWING THE WORLD IN A DOCUMENTARY FILM AMISH ON BREAK [PDF]

open access: yes, 2014
Agama telah menjadi ulasan menarik disetiap negara sejak dulu kala tak terkecuali di Amerika Serikat. Agama juga seolah sudah menjadi bagian penting di dalam kehidupan bermasyarakat dan berbudaya.
Purwaningsih, Siti
core   +1 more source

The condition of the working class: Representation and praxis [PDF]

open access: yes, 2013
Copyright © 2013 Immanuel Ness and Wiley Periodicals, Inc. This is the accepted version of the following article: Wayne, M. and O'Neill, D. (2013), The Condition of the Working Class: Representation and Praxis.
Benjamin   +19 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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