Results 61 to 70 of about 373,604 (293)

Broadcasting graphic war violence: the moral face of Channel 4 [PDF]

, 2013
Drawing on empirical data from Channel 4 (C4) regarding the broadcasting of violent war imagery, and positioned within Goffman’s notion of the interaction ritual (1959, 1967), this article investigates how C4 negotiate potentially competing commercial ...
BBC2, Blumer H, Born G, Born G, BSC, Butler J, C4, Dornfeld B, Dworkin R, Emerson R, Frost C, Garfinkel H, Gill R, Goffman E, Goffman E, Hall S, Hawkins K, Hawkins K, Johnson C, Maltby S, Manning P, Pekurny R, Richardson G, Steemers J, Tester K   +24 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The documentary evidence for Templar religion [PDF]

, 2017
The Templar Rule and statutes are also only of limited help when it comes to establishing what went on within the walls of Templar churches. The documentary evidence that captures the patchwork nature of Templar religion best is found in the Templar ...
Schenk, Jochen
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Palliative care: A proposal for undergraduate education in Medicine

Revista Brasileira de Geriatria e Gerontologia, 2018
Objective: to propose essential competencies for the teaching of palliative care on undergraduate Medicine courses. Method: a documentary analysis of the literature on general competencies in palliative care was initially carried out, to construct a ...
Gustavo Henrique de Oliveira Caldas, Simone de Nóbrega Tomaz Moreira, Maria José Vilar   +2 more
doaj   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

THE IMPORTANCE OF THE TOWN GALATZ IN THE ECONOMIC DEVELOPMENT OF MOLDAVIA DURING THE FIRST HALF OF THE NINETEENTH CENTURY

Journal of Industrial Design and Engineering Graphics, 2014
The purpose of this paper is to present the activity of foreigners in the port city of Galatz, during the first half of the 19th century. Consulted material included documentary sources, monographs, and historical synthesis.
CHEŞCU Ana-Maria
doaj  

Transnationality and transitionality in Sandra Kogut´s "The Hungarian Passport" [PDF]

, 2011
This article examines Sandra Kogut’s The Hungarian Passport (2001) in the light of recent theoretical debates on diasporic and postcolonial filmmaking. It focuses on how Kogut’s displacement—both as the granddaughter of Jewish refugees and a foreigner in
Pinazza, Natalia
core  

Documental Survey of Project Prim’art - Portugal Rediscovering Mural Art: Historical and Scientific Study Of Archiepiscopal Évora [PDF]

, 2015
The importance of documentary research for art history studies in Cultural Heritage is unquestionable to ascertain the date of a masterpiece, confirmation of authorship and acknowledgement or dismissal of its historical theories.
Araújo, Custódia, Conde, Antónia Fialho, Gil, Milene   +2 more
core   +1 more source