Results 121 to 130 of about 1,289,776 (315)

Revitalizing education in rural and small schools: The role of AI in teachers' professional development

open access: yesItalian Journal of Educational Technology
The article explores the intersection of artificial intelligence (AI) and the professional development of teachers, with a focus on small and rural schools.
Giuseppina Rita Jose Mangione   +2 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

FID news bulletin.

open access: yes, 1951
Mode of access: Internet.Contains administrative material and news formerly published in Revue de la ...
International Federation for Documentation.
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Bulletin de la documentation collégiale numéro 18

open access: yes, 2017
Disponible en anglais dans EDUQ.info sous le titre "The Inclusion of Students with Disabilities in Quebec Colleges"Comprend des références bibliographiquesDans les établissements postsecondaires du Québec, le nombre d’étudiants en situation de handicap ...
Havel, Alice, Raymond, Odette
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

College documentation bulletin

open access: yes, 2009
Comprend des références bibliographiquesDisponible en français dans EDUQ.info sous le titre "Bulletin de la documentation ...

core  

Histoire de la documentation en France

open access: yes, 2000
À la fin du XIXe siècle, l’information devenant pléthorique, les méthodes et les outils permettant de repérer et de retrouver l’information deviennent incontournables pour maîtriser l’accès au savoir.
Fayet-Scribe, Sylvie
core   +1 more source

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