Results 161 to 170 of about 612,079 (291)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Smart Paper Technology for maternal and newborn health data in The Gambia: A qualitative study of early implementation. [PDF]

open access: yesPLOS Glob Public Health
Nkereuwem O   +10 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Evaluating an LLM-assisted workflow for clinical documentation: A pilot randomized controlled trial on time and quality. [PDF]

open access: yesPLOS Digit Health
Takayama T   +12 more
europepmc   +1 more source

AID---access to informal documentation [PDF]

open access: yesProceedings of the 12th annual ACM SIGUCCS conference on User services - SIGUCCS '84, 1984
openaire   +2 more sources

Recommendations for Dealing with Unexpected Challenges in Paying Back Documentation Debt

open access: yes
Technical debt has become a significant concern for organizations that accumulate increasingly complex information systems architectures. Broadly defined as future system-maintenance obligations, technical debt comes in various forms.
Rinta-Kahila, Tapani   +3 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

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