Results 11 to 20 of about 37,513 (176)

Oral transmission of Chagas disease from a One Health approach: A systematic review

Tropical Medicine &International Health, Volume 28, Issue 9, Page 689-698, September 2023., 2023
Abstract Objective To analyse acute Chagas disease (CD) outbreaks through a qualitative systematic review and discuss the determinants for its prevention and control. Methods Review of studies in which clinical cases of oral transmission were confirmed by parasitological and/or serological tests that included an epidemiological investigation of sources
Alejandra López‐García, Juan A. Gilabert   +1 more
wiley   +1 more source

Senescent T cells: Beneficial and detrimental roles

Immunological Reviews, Volume 316, Issue 1, Page 160-175, July 2023., 2023
Summary As the thymus involutes during aging, the T‐cell pool has to be maintained by the periodic expansion of preexisting T cells during adulthood. A conundrum is that repeated episodes of activation and proliferation drive the differentiation of T cells toward replicative senescence, due to telomere erosion.
Phatthamon Laphanuwat, Daniel Claudio Oliveira Gomes, Arne N. Akbar   +2 more
wiley   +1 more source

Suppression of TGF‐β/Smad2 signaling by GW788388 enhances DENV‐2 clearance in macrophages

Journal of Medical Virology, Volume 94, Issue 9, Page 4359-4368, September 2022., 2022
Abstract Dengue fever, caused by the dengue virus (DENV‐1, −2, −3, and −4), affects millions of people in the tropical and subtropical regions worldwide. Severe dengue is correlated with high viraemia and cytokine storm, such as high levels of transforming growth factor‐β1 (TGF‐β1) in the patient's serum.
Gabrielly Sbano Teixeira, Audrien Alves Andrade, Lauana Ribas Torres, Dinair Couto‐Lima, Otacilio C. Moreira, Rayane Abreu, Mariana Caldas Waghabi, Elen Mello de Souza   +7 more
wiley   +1 more source

Effects of anti‐Leishmania compounds in the behavior of the sand fly vector Lutzomyia longipalpis

Pest Management Science, Volume 78, Issue 7, Page 2792-2805, July 2022., 2022
Sugar baits can be used to block the development of Leishmania parasites inside the gut of the vector, adult female sand flies. In this work, we screened a series of synthetic compounds and showed that three of them are suitable for the future development of baits targeting the Leishmania parasites inside the sand fly Lutzomyia longipalpis.
Tainá Neves Ferreira, Reginaldo Peçanha Brazil, Mary Ann McDowell, Edézio Ferreira Cunha‐Júnior, Paulo Roberto Ribeiro Costa, Chaquip Daher Netto, Eduardo Caio Torres Santos, Fernando Ariel Genta   +7 more
wiley   +1 more source

Cryptococcus extracellular vesicles properties and their use as vaccine platforms

Journal of Extracellular Vesicles, Volume 10, Issue 10, August 2021., 2021
Abstract Whereas extracellular vesicle (EV) research has become commonplace in different biomedical fields, this field of research is still in its infancy in mycology. Here we provide a robust set of data regarding the structural and compositional aspects of EVs isolated from the fungal pathogenic species Cryptococcus neoformans, C. deneoformans and C.
Juliana Rizzo, Sarah Sze Wah Wong, Anastasia D. Gazi, Frédérique Moyrand, Thibault Chaze, Pierre‐Henri Commere, Sophie Novault, Mariette Matondo, Gérard Péhau‐Arnaudet, Flavia C. G. Reis, Matthijn Vos, Lysangela R. Alves, Robin C. May, Leonardo Nimrichter, Marcio L. Rodrigues, Vishukumar Aimanianda, Guilhem Janbon   +16 more
wiley   +1 more source

Combining Well‐Tempered Metadynamics Simulation and SPR Assays to Characterize the Binding Mechanism of the Universal T‐Lymphocyte Tetanus Toxin Epitope TT830‐843

BioMed Research International, Volume 2021, Issue 1, 2021., 2021
Peptide TT830‐843 from the tetanus toxin is a universal T‐cell epitope. It helps in vaccination and induces T‐cell activation. However, the fine molecular interaction between this antigen and the major histocompatibility complex (MHC) remains unknown.
Artur A. M. L. Brandt, Rodrigo N. Rodrigues-da-Silva, Josué C. Lima-Junior, Carlos R. Alves, Franklin de Souza-Silva, Sebastien Fiorucci   +5 more
wiley   +1 more source

Comparação entre acalásia idiopática e acalásia conseqüente à doença de Chagas: revisão de publicações sobre o tema [PDF]

Arquivos de Gastroenterologia, 2003
RACIONAL: Embora acalásia idiopática e acalásia conseqüente à doença de Chagas tenham manifestações clínicas semelhantes, mesmo tratamento e ambas comprometerem o plexo mientérico do esôfago, é possível que as alterações motoras do esôfago provocadas ...
Roberto Oliveira Dantas
doaj   +1 more source

Patterns of antenal sensilla of Panstrongylus megistus from three Brazilian states [PDF]

, 2005
The objective of the present study was to analyze and describe the phenotype of the antennal sensilla of Panstrongylus megistus, one of the epidemiologically most important species of triatomines in Brazil.
Catala, Silvia Susana, Dias, J. C. P., Juberg, J., Silva, I. G., Villela, M. M.   +4 more
core   +1 more source

Integrated control of chagas disease for its elimination as public health problem: A review [PDF]

, 2015
Chagas disease or American trypanosomiasis is, together with geohelminths, the neglected disease that causes more loss of years of healthy life due to disability in Latin America.
Segura, Elsa Leonor, Sosa-Estani, Sergio Alejandro   +1 more
core   +4 more sources

Markers for the population genetics studies of Triatoma sordida (Hemiptera: Reduviidae)

Parasites & Vectors, 2015
Background Triatoma sordida, a vector of Trypanosoma cruzi, is native of Brazil, Bolivia, Paraguay, Argentina, and Uruguay, and occurs primarily in peridomiciles. Currently, it is the species most frequently captured by the Chagas Disease Control Program
Carlota Josefovicz Belisário, Grasielle Caldas D’Ávila Pessoa, Paula Fernandes dos Santos, Letícia Sena Dias, Aline Cristine Luiz Rosa, Liléia Diotaiuti   +5 more
doaj   +1 more source