Results 1 to 10 of about 10,024 (152)

Fatal CTLA‐4 heterozygosity with autoimmunity and recurrent infections: a de novo mutation [PDF]

Clinical Case Reports, 2017
Key Clinical Message Primary immunodeficiency disorders are rarely diagnosed in adults but must be considered in the differential diagnosis of combined recurrent infections and autoimmune disease.
Maria Francisca Moraes‐Fontes, Amy P. Hsu, Iris Caramalho, Catarina Martins, Ana Carolina Araújo, Filipa Lourenço, Anna V. Taulaigo, Ana Lladó, Steven M. Holland, Gulbu Uzel   +9 more
doaj   +3 more sources

Primary Anti-Phospholipid Antibody Syndrome: Real-World Defining Features of Rethrombosis in the Course of Disease. [PDF]

Int J Rheumatol, 2022
Objective. We aimed to identify features that allow differentiation of primary antiphospholipid syndrome (PAPS) patients that suffer recurrent thrombotic events (RTE) despite anticoagulation, from the other diagnosed PAPS patients. Methods. This was an exploratory study of anticoagulated PAPS patients attending an Autoimmune Diseases Unit (1998‐2018 ...
Moraes-Fontes MF, Pedro F, Campos MM, Fernandes M, Yavuz S, Oliveira F, Panarra A.   +6 more
europepmc   +2 more sources

Complex antiphospholipid syndrome successfully controlled for 17 years with personalized enoxaparin therapy [PDF]

European Journal of Case Reports in Internal Medicine
Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by the presence of antiphospholipid antibodies and venous and arterial thrombotic events, including obstetric complications.
Mafalda Vasconcelos, Patrícia Moreira, Teresa Costa e Silva, João Espírito Santo, Carla Noronha   +4 more
doaj   +2 more sources

Determinant Factors of Morbidity in Patients with Systemic Lupus Erythematosus [PDF]

Acta Médica Portuguesa, 2017
Introduction: Severity in systemic lupus erythematosus may vary from mild to even fatal consequences. There are no biomarkers to predict the disease’s prognosis.
Margarida Jacinto, Eliana Silva, Nuno Riso, Maria Francisca Moraes-Fontes   +3 more
doaj   +4 more sources

Vaccination of Adult Patients with Systemic Lupus Erythematosus in Portugal. [PDF]

Int J Rheumatol, 2016
In the wake of the Portuguese vaccination program 50th anniversary it seems appropriate to review vaccination in patients with systemic lupus erythematosus. Controversial issues as regards the association between autoimmune diseases, infections, and vaccines are discussed as well as vaccine safety and efficacy issues as regards chronic ...
Moraes-Fontes MF, Antunes AM, Gruner H, Riso N.   +3 more
europepmc   +2 more sources

Neuropsychiatric features of a cohort of patients with systemic lupus erythematosus. [PDF]

ISRN Rheumatol, 2012
In order to establish if neuropsychiatric systemic lupus erythematosus (NPSLE) can be identified by any characteristic other than those used to diagnose the neuropsychiatric (NP) disease itself, we retrospectively reviewed 98 systemic lupus erythematosus (SLE) patients followed over a mean period of 10 years. NPSLE was identified in 22 patients. Stroke
Moraes-Fontes MF, Lúcio I, Santos C, Campos MM, Riso N, Vaz Riscado M.   +5 more
europepmc   +2 more sources

Neurodegeneration in systemic lupus erythematosus: layer by layer retinal study using optical coherence tomography [PDF]

International Journal of Retina and Vitreous, 2020
Background Systemic lupus erythematosus (SLE) is a chronic, autoimmune and multisystemic disease. Recent studies with functional and structural magnetic resonance imaging and cognitive tests report an unexpectedly high frequency of central nervous system
Arnaldo Dias-Santos, Joana Tavares Ferreira, Sofia Pinheiro, João Paulo Cunha, Marta Alves, Ana L. Papoila, Maria Francisca Moraes-Fontes, Rui Proença   +7 more
doaj   +2 more sources

Células T regulatórias naturais (T REGS) em doenças reumáticas Natural regulatory T cells in rheumatic diseases [PDF]

Revista Brasileira de Reumatologia, 2008
O sistema imune sadio deve manter o balanço entre a capacidade de responder a agentes infecciosos e de sustentar a autotolerância. A ausência de resposta adequada submete o indivíduo aos efeitos deletérios da invasão por patógenos, ao passo que o sistema
Wilson de Melo Cruvinel, Danilo Mesquita Jr., Júlio Antônio Pereira Araújo, Karina Carvalho Salmazi, Esper Georges Kállas, Luis Eduardo Coelho Andrade   +5 more
doaj   +4 more sources

Ultrasound detects subclinical joint inflammation in the hands and wrists of patients with systemic lupus erythematosus without musculoskeletal symptoms. [PDF]

Lupus Sci Med, 2017
OBJECTIVES: To assess the prevalence and severity of ultrasonographic abnormalities of the hand and wrist of asymptomatic patients with systemic lupus erythematosus (SLE) and compare these findings with those from patients with SLE with musculoskeletal ...
Ruano CA, Malheiro R, Oliveira JF, Pinheiro S, Vieira LS, Moraes-Fontes MF.   +5 more
europepmc   +3 more sources

Heterogeneous lupus-specific lesions and treatment outcome, in a single patient, over a period of time. [PDF]

Clin Case Rep, 2019
The report highlights the importance of strict clinico-histological correlations when skin biopsies are performed in diagnostic doubt in systemic lupus erythematosus.
Fernandes M, Taulaigo AV, Vidal C, Agostini P, Riso N, Moraes-Fontes MF.   +5 more
europepmc   +4 more sources