Macroanatomical, Histological, Histochemical and Ultrastructural Characterisation of the Kidney in the Aksaray Malakli Dog: First Comprehensive Renal Morphological Study of the Breed. [PDF]
Vet Med SciKuloğlu HY +3 more
europepmc +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
The vacuum effect in free-roaming dog management: Conceptual foundations, boundary conditions, and One Health implications. [PDF]
One HealthPathak A +5 more
europepmc +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Letter from James Black Dog to Representative Burdick Regarding Tribal Funds, April 18, 1957
, 1957 This letter, dated April 18, 1957, from James Black Dog of Emmet, North Dakota to United States (US) Representative Usher Burdick raises questions about tribal funds of the Three Affiliated Tribes of the Fort Berthold Reservation, particularly segregated
Black Dog, James
core
Dog Bite Epidemiology and Postexposure Practices Among Dog Owners in Some Communities in the Upper West Region of Ghana. [PDF]
J Trop MedSuu-Ire RD +11 more
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
A mixed-methods feasibility study of dog-assisted exercise therapy in geriatric inpatients. [PDF]
BMC GeriatrJoschko L +5 more
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Veterinary student wellbeing and its relationship with dog handling and fear responses during a clinical examination laboratory. [PDF]
Front Vet SciNakonechny L +3 more
europepmc +1 more source