Results 101 to 110 of about 229,011 (298)
Suggesting Cooking Recipes Through Simulation and Bayesian Optimization
, 2018 Cooking typically involves a plethora of decisions about ingredients and tools that need to be chosen in order to write a good cooking recipe. Cooking can be modelled in an optimization framework, as it involves a search space of ingredients, kitchen ...
B Shahriari +3 more
core +1 more source
Extracting Product Performance by Embedding Sensors in SFF Prototypes [PDF]
, 2004 SFF has been instrumental in improving the design process by providing designers with prototypes that assist them in the communication of design information and design visualization prior to creating fully functional prototypes.
Campbell, Matthew +2 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
PLoS ONEThe owner-dog relationship is a critical component of sustained dog ownership. Increased understanding of risk factors for weak owner-dog relationships can identify owner-dog dyads at higher risk of poor welfare outcomes, including dog relinquishment and
Bree L Merritt +6 more
doaj +1 more source
Large Dog Relinquishment to Two Municipal Facilities in New York City and Washington, D.C.: Identifying Targets for Intervention [PDF]
, 2014 While the overall trend in euthanasia has been decreasing nationally, large dogs are at a higher risk of euthanasia than other sized dogs in most animal shelters in the United States.
Emily Dolan +6 more
core +3 more sources
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
An uncommon localisation of a vegetal foreign body in a dog: a case report
Veterinární Medicína, 2017 The goal of this study was to describe the ultrasonographic and computed tomographic appearance of a penile foreign body in a dog for the first time.
F. Del Signore +9 more
doaj +1 more source
Acquisition in the course of conversation [PDF]
, 1999 published or submitted for publicationis peer ...
Clark, Eve V.
core
The Emerging Nature of Participation in Multispecies Interaction Design [PDF]
, 2018 Interactive technology has become integral part of daily life for both humans and animals, with animals often interacting with technologized environments on behalf of humans.
Haraway D. +4 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source