Results 71 to 80 of about 210,714 (296)

The demography of free-roaming dog populations and applications to disease and population control [PDF]

, 2014
Understanding the demography of domestic dog populations is essential for effective disease control, particularly of canine-mediated rabies. Demographic data are also needed to plan effective population management.
Cleaveland, Sarah, Conlan, Andrew J.K., Damriyasa, I. Made, Hampson, Katie, McCallum, Hamish, McKinley, Trevelyan J., Morters, Michelle K., Restif, Olivier, Whay, Helen R., Wood, James L.N.   +9 more
core   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Why Do People Choose a Particular Dog? A Mixed-Methods Analysis of Factors Owners Consider Important When Acquiring a Dog, on a Convenience Sample of Austrian Pet Dog Owners

Animals
Selecting a dog that is incompatible with the owner’s expectations can negatively impact both parties. Previous studies on dog acquisition have primarily focused on shelter environments, using closed-ended questions to assess hypothetical preferences. In
Kata Mária Udvarhelyi-Tóth, Ivaylo B. Iotchev, Eniko Kubinyi, Borbála Turcsán   +3 more
doaj   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

What Do We Know about Dog Owners? Exploring Associations between Pre-Purchase Behaviours, Knowledge and Understanding, Ownership Practices, and Dog Welfare

Animals
Despite many dogs living in homes in the UK, there is still more to know about the welfare of those individual animals. Past research has shown that owners’ thoughts and behaviours have a substantial impact on their dog’s welfare.
Izzie Philpotts, Emily J. Blackwell, Justin Dillon, Emma Tipton, Nicola J. Rooney   +4 more
doaj   +1 more source

Point Mutations in the Glycoprotein Ectodomain of Field Rabies Viruses Mediate Cell Culture Adaptation through Improved Virus Release in a Host Cell Dependent and Independent Manner

Viruses, 2021
Molecular details of field rabies virus (RABV) adaptation to cell culture replication are insufficiently understood. A better understanding of adaptation may not only reveal requirements for efficient RABV replication in cell lines, but may also provide ...
Sabine Nitschel, Luca M. Zaeck, Madlin Potratz, Tobias Nolden, Verena te Kamp, Kati Franzke, Dirk Höper, Florian Pfaff, Stefan Finke   +8 more
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Parameter identification for coupled elasto-plasto-damage model for overheated concrete

MATEC Web of Conferences, 2017
The methodology of experimental acquisition and subsequent processing of data for identification of nonlinear elasto-plasto-damage concrete model parameters are considered. Typical measurement equipment and data acquisition process are described.
Benin Andrey, Semenov Sergey, Semenov Artem, Bogdanova Galina   +3 more
doaj   +1 more source

Acquired multi-azole resistance in Candida tropicalis during persistent urinary tract infection in a dog

Medical Mycology Case Reports, 2016
Multi-azole resistance acquisition by Candida tropicalis after prolonged antifungal therapy in a dog with urinary candidiasis is reported. Pre- and post-azole treatment isolates were clonally related and had identical silent mutations in the ERG11 gene ...
Sergio Álvarez-Pérez, Marta E. García, María Teresa Cutuli, María Luisa Fermín, María Ángeles Daza, Teresa Peláez, José L. Blanco   +6 more
doaj   +1 more source

The Interaction of Memory and Attention in Novel Word Generalization: A Computational Investigation [PDF]

, 2016
People exhibit a tendency to generalize a novel noun to the basic-level in a hierarchical taxonomy -- a cognitively salient category such as "dog" -- with the degree of generalization depending on the number and type of exemplars.
Grant, Erin, Nematzadeh, Aida, Stevenson, Suzanne   +2 more
core   +1 more source