Mathematical model to assess the impact of contact rate and environment factor on transmission dynamics of rabies in humans and dogs [PDF]
This paper presents a mathematical model to understand how rabies spreads among humans, free-range, and domestic dogs. By analyzing the model, we discovered that there are equilibrium points representing both disease-free and endemic states. We calculated the basic reproduction number, $\mathcal{R}_{0}$, using the next generation matrix method.
arxiv +1 more source
Myotubularin MTM1 Involved in Centronuclear Myopathy and its Roles in Human and Yeast Cells [PDF]
Mutations in the MTM1 gene, encoding the phosphoinositide phosphatase myotubularin, are responsible for the X-linked centronuclear myopathy (XLCNM) or X-linked myotubular myopathy (XLMTM). The MTM1 gene was first identified in 1996 and its function as a PtdIns3P and PtdIns(,5)P2 phosphatase was discovered in 2000.
arxiv +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Sistem Pakar Identifikasi Penyakit Kulit Anjing Menggunakan Metode Certainty Factor [PDF]
Dogs are common animal that found as pets in Indonesia. Indonesia as a tropical country has a high humidity, where fungi and parasites easily to multiply on animal skin. The fungi and parasites are one of the causes of dog skin diseases.
Hakim, A. M. (Arnaz)+2 more
core
A One Health Framework for the Evaluation of Rabies Control Programmes: A Case Study from Colombo City, Sri Lanka [PDF]
BackgroundOne Health addresses complex challenges to promote the health of all species and the environment by integrating relevant sciences at systems level.
Barbara Häsler+34 more
core +2 more sources
The effectiveness of treatment for dirofilariasis in dogs
Livestock industry – dog breeding is of great importance in human activities. Infectious and invasive diseases are a deterrent to the breeding and improvement of dog breeds. Not only do they cause significant economic damage to dog breeding, but they can
D. Kryvoruchenko
doaj +1 more source
The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
First report of highly pathogenic Echinococcus granulosus genotype G1 in dogs in a European urban environment [PDF]
BACKGROUND: Echinococcus granulosus and E. multilocularis are tapeworm parasites of major medical and veterinary importance, causing cystic and alveolar echinococcosis, respectively.
Epp Moks+13 more
core +1 more source
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression
Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song+11 more
wiley +1 more source