Results 71 to 80 of about 9,684,425 (379)

A working model for cytoplasmic assembly of H/ACA snoRNPs

open access: yesFEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Epidemiologia de problemas comportamentais em cães no Brasil: inquérito entre médicos veterinários de pequenos animais Epidemiology of dogs behavioral problems in Brazil: a survey between small animals veterinary practitioners

open access: yesCiência Rural, 2010
Problemas de comportamento afetam diretamente a qualidade de vida dos animais e das pessoas que com eles convivem. Em alguns países, os problemas de comportamento são as principais causas de abandono e eutanásia de animais de companhia. O presente estudo
Guilherme Marques Soares   +3 more
doaj  

Approaches to canine health surveillance [PDF]

open access: yes, 2014
Effective canine health surveillance systems can be used to monitor disease in the general population, prioritise disorders for strategic control and focus clinical research, and to evaluate the success of these measures.
Brodbelt, D C   +5 more
core   +2 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

The effectiveness of treatment for dirofilariasis in dogs

open access: yesНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2022
Livestock industry – dog breeding is of great importance in human activities. Infectious and invasive diseases are a deterrent to the breeding and improvement of dog breeds. Not only do they cause significant economic damage to dog breeding, but they can
D. Kryvoruchenko
doaj   +1 more source

Largest dog genetic study informs human diseases [PDF]

open access: yes, 2016
The news item from the Cornell Chronicle is about: Cornell researchers have completed the largest genetic study of dogs to date, comprising the genetic analysis of 4,200 dogs.
Office of Marketing and Communications. Media Relations
core  

Transmission dynamics and prospects for the elimination of canine rabies [PDF]

open access: yes, 2009
Rabies has been eliminated from domestic dog populations in Western Europe and North America, but continues to kill many thousands of people throughout Africa and Asia every year.
Cleaveland, S.   +7 more
core   +5 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Dog assisted education in children with rheumatic diseases and adolescents with chronic pain in Germany

open access: yesGMS Journal for Medical Education, 2023
Objectives: Animal assisted intervention is an increasingly accepted tool to improve human well-being. The present study was performed to assess whether dog assisted education has a positive effect on children suffering from rheumatic disorders with pain
Kiesewetter, Jan   +9 more
doaj   +1 more source

Dogs Never Gets Prion Diseases. The Entropic Landscape Analysis of Prion Proteins Answers Why. [PDF]

open access: yes, 2009
The Entropic Landscape Analysis was applied to the prion protein sequences of various mammals in order to detect potential sites of variants that would be responsible for the susceptibility of prion disease infection.
Kentaro Onizuka
core   +1 more source

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