Results 71 to 80 of about 9,518,717 (373)

Analyzing large-scale DNA Sequences on Multi-core Architectures

open access: yes, 2015
Rapid analysis of DNA sequences is important in preventing the evolution of different viruses and bacteria during an early phase, early diagnosis of genetic predispositions to certain diseases (cancer, cardiovascular diseases), and in DNA forensics ...
Memeti, Suejb, Pllana, Sabri
core   +1 more source

The risk of rabies spread in Japan: a mathematical modeling assessment [PDF]

open access: yes, 2018
Rabies was eliminated from Japan in 1957. In the 60 years since elimination, vaccination coverage has declined and dog ownership habits have changed. The purpose of this study was to assess the current risk of rabies spread in Japan. A spatially explicit
Hampson, K.   +4 more
core   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Reconciling surveillance systems with limited resources: an evaluation of passive surveillance for rabies in an endemic setting [PDF]

open access: yes, 2015
Surveillance systems for rabies in endemic regions are often subject to severe constraints in terms of resources. The World Organisation for Animal Health (OIE) and the World Health Organisation (WHO) propose the use of an active surveillance system to ...
Barbara Häsler   +23 more
core   +2 more sources

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Epidemiologia de problemas comportamentais em cães no Brasil: inquérito entre médicos veterinários de pequenos animais Epidemiology of dogs behavioral problems in Brazil: a survey between small animals veterinary practitioners

open access: yesCiência Rural, 2010
Problemas de comportamento afetam diretamente a qualidade de vida dos animais e das pessoas que com eles convivem. Em alguns países, os problemas de comportamento são as principais causas de abandono e eutanásia de animais de companhia. O presente estudo
Guilherme Marques Soares   +3 more
doaj  

The effectiveness of treatment for dirofilariasis in dogs

open access: yesНауковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2022
Livestock industry – dog breeding is of great importance in human activities. Infectious and invasive diseases are a deterrent to the breeding and improvement of dog breeds. Not only do they cause significant economic damage to dog breeding, but they can
D. Kryvoruchenko
doaj   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Largest dog genetic study informs human diseases [PDF]

open access: yes, 2016
The news item from the Cornell Chronicle is about: Cornell researchers have completed the largest genetic study of dogs to date, comprising the genetic analysis of 4,200 dogs.
Office of Marketing and Communications. Media Relations
core  

Wolf outside, dog inside? The genomic make-up of the Czechoslovakian Wolfdog [PDF]

open access: yes, 2018
Background Genomic methods can provide extraordinary tools to explore the genetic background of wild species and domestic breeds, optimize breeding practices, monitor and limit the spread of recessive diseases, and discourage illegal crossings.
Bolf\uedkov\ue1, Barbora \u10cern\ue1   +10 more
core   +2 more sources

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