Results 31 to 40 of about 26,965 (149)

Estimation of the size, density, and demographic distribution of the UK pet dog population in 2019

Scientific Reports
There is limited knowledge about the size of the UK dog population. This makes it difficult to reliably monitor population dynamics and management. A repeatable method of measuring the UK dog population, including owned and unowned dogs i.e., those ...
Kirsten M. McMillan, Xavier A. Harrison, David C. Wong, Melissa M. Upjohn, Robert M. Christley, Rachel A. Casey   +5 more
doaj   +1 more source

Serum symmetric dimethylarginine concentration in healthy horses and horses with acute kidney injury

BMC Veterinary Research, 2020
Background There are limited options to diagnose acute kidney injury (AKI) in horses. Symmetric dimethylarginine (SDMA) is routinely used in human and small animal medicine.
Natalia Siwinska, Agnieszka Zak, Malwina Slowikowska, Artur Niedzwiedz, Urszula Paslawska   +4 more
doaj   +1 more source

Detecting acute kidney injury in horses by measuring the concentration of symmetric dimethylarginine in serum

Acta Veterinaria Scandinavica, 2021
Background Acute kidney injury (AKI) in horses may develop as a complication of a primary disease or following the administration of nephrotoxic drugs, and may pose a diagnostic challenge.
Natalia Siwinska, Agnieszka Zak, Urszula Paslawska   +2 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

New Strategies of Canine Post-Adoption Support: Methods for a Prospective Longitudinal Cohort Study

Animals
In 2018, Dogs Trust (UK) launched the Post Adoption Support project, the largest known prospective cohort study investigating behavioural and health problems post-rehoming of dogs.
Emma L. Buckland, Kassandra Giragosian, Eleanor J. Jordan, Rosa E. P. Da Costa, Joshua L. Woodward, Rachel A. Casey   +5 more
doaj   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Acquiring a Pet Dog: A Review of Factors Affecting the Decision-Making of Prospective Dog Owners

Animals, 2019
Given the prevalence of pet dogs in households throughout the world, decisions regarding dog acquisition affect many people each year. Across the stages of dog acquisition there is potential for practices that may promote or compromise canine welfare ...
Katrina E. Holland
doaj   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

Molecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink, Leon W. M. M. Terstappen, Eshwari Dathathri, Khrystany Isebia, Jaco Kraan, John Martens, Ruchi Bansal   +6 more
wiley   +1 more source

UK Dog Owners’ Pre-Acquisition Information- and Advice-Seeking: A Mixed Methods Study

Animals
Dogs are the most common pet animal species in the UK. Little is known about information and advice gathering within the process of dog acquisition, nor what pre-acquisition research encompasses.
Rebecca Mead, Katrina E. Holland, Rachel A. Casey, Melissa M. Upjohn, Robert M. Christley   +4 more
doaj   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source