Results 111 to 120 of about 389,599 (264)
Applied SciencesFew-shot domain adaptation (FSDA) has become an important approach for cross-domain intrusion detection by enabling models to leverage limited labeled target data under distribution shifts.
Kangseok Kim
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Improved triplet loss for domain adaptation
IET Computer VisionA technique known as domain adaptation is utilised to address classification challenges in an unlabelled target domain by leveraging labelled source domains.
Xiaoshun Wang +2 more
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Style Adaptation for Domain-Adaptive Semantic Segmentation
ICASSP 2024 - 2024 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)Unsupervised Domain Adaptation (UDA) refers to the method that utilizes annotated source domain data and unlabeled target domain data to train a model capable of generalizing to the target domain data. Domain discrepancy leads to a significant decrease in the performance of general network models trained on the source domain data when applied to the ...
Ting Li, Jianshu Chao, Deyu An
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Physics informed spectrogram normalization and domain adaptation for intermittent fault diagnosis
Discover Applied SciencesIntermittent faults are characterized by short duration and random occurrence. They are often missed by machine learning models trained exclusively on permanent fault data.
Sunil Nag P. V, C. Santhosh Kumar
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