Results 71 to 80 of about 549,366 (277)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Episodic Training and Feature Orthogonality-Driven Domain Generalization for Rotating Machinery Fault Diagnosis Under Unseen Working Conditions

Machines
In recent years, domain generalization-based fault diagnosis (DGFD) methods have shown significant potential in rotating machinery fault diagnosis in unseen target domains.
Yixiao Liao, Songbin Zhou, Yisen Liu, Kunkun Pang, Jing Li, Chang Li, Lulu Zhao   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Complexity over Uncertainty in Generalized Representational\ud Information Theory (GRIT): A Structure-Sensitive General\ud Theory of Information [PDF]

, 2013
What is information? Although researchers have used the construct of information liberally to refer to pertinent forms of domain-specific knowledge, relatively few have attempted to generalize and standardize the construct.
Vigo, Professor Ronaldo
core  

Clifford Fourier-Mellin transform with two real square roots of -1 in Cl(p,q), p+q=2

, 2012
We describe a non-commutative generalization of the complex Fourier-Mellin transform to Clifford algebra valued signal functions over the domain $\R^{p,q}$ taking values in Cl(p,q), p+q=2.
Hitzer, Eckhard
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Domain Generalization Through Data Augmentation: A Survey of Methods, Applications, and Challenges

Mathematics
Domain generalization (DG) has become a pivotal research area in machine learning, focusing on equipping models with the ability to generalize effectively to unseen test domains that differ from the training distribution.
Junjie Mai, Chongzhi Gao, Jun Bao
doaj   +1 more source

Transfer Metric Learning for Unseen Domains

Data Science and Engineering, 2020
We propose a transfer metric learning method to infer domain-specific data embeddings for unseen domains, from which no data are given in the training phase, by using knowledge transferred from related domains.
Atsutoshi Kumagai, Tomoharu Iwata, Yasuhiro Fujiwara   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source