Results 81 to 90 of about 549,366 (277)

Wasserstein Distance Guided Representation Learning for Domain Adaptation

open access: yes, 2018
Domain adaptation aims at generalizing a high-performance learner on a target domain via utilizing the knowledge distilled from a source domain which has a different but related data distribution.
Qu, Yanru   +3 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Open DGML: Intrusion Detection Based on Open-Domain Generation Meta-Learning

open access: yesApplied Sciences
Network security is crucial for national infrastructure, but the increasing number of network intrusions poses significant challenges. To address this issue, we propose Open DGML, a framework based on open-domain generalization meta-learning for ...
Kaida Jiang   +4 more
doaj   +1 more source

Soft Prompt Generation for Domain Generalization

open access: yes
Large pre-trained vision language models (VLMs) have shown impressive zero-shot ability on downstream tasks with manually designed prompt. To further adapt VLMs to downstream tasks, soft prompt is proposed to replace manually designed prompt, which undergoes fine-tuning based on specific domain data.
Bai, Shuanghao   +4 more
openaire   +2 more sources

Domain Generalization for Domain-Linked Classes

open access: yes, 2023
Domain generalization (DG) focuses on transferring domain-invariant knowledge from multiple source domains (available at train time) to an, a priori, unseen target domain(s). This requires a class to be expressed in multiple domains for the learning algorithm to break the spurious correlations between domain and class.
Kaai, Kimathi   +2 more
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

DANSK: Domain Generalization of Danish Named Entity Recognition

open access: yesNorthern European Journal of Language Technology
Named entity recognition is an important application within Danish NLP, essential within both industry and research. However, Danish NER is inhibited by a lack coverage across domains and entity types.
Kenneth Enevoldsen   +2 more
doaj   +1 more source

The Peierls-Nabarro model as a limit of a Frenkel-Kontorova model [PDF]

open access: yes, 2010
We study a generalization of the fully overdamped Frenkel-Kontorova model in dimension $n\geq 1.$ This model describes the evolution of the position of each atom in a crystal, and is mathematically given by an infinite system of coupled first order ODEs.
Fino, Ahmad   +2 more
core   +5 more sources

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