Results 81 to 90 of about 1,290,938 (334)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Statistical Study of the Bias and Precision for Six Estimation Methods for the Fractal Dimension of Randomly Rough Surfaces

Fractal and Fractional
The simulation and characterisation of randomly rough surfaces is an important topic in surface science, tribology, geo- and planetary sciences, image analysis and optics.
Jorge Luis Flores Alarcón, Carlos Gabriel Figueroa, Víctor Hugo Jacobo, Fernando Velázquez Villegas, Rafael Schouwenaars   +4 more
doaj   +1 more source

BadDGA: Backdoor Attack on LSTM-Based Domain Generation Algorithm Detector [PDF]

, 2023
You Zhai, Liqun Yang, Jian Yang, Longtao He, Zhoujun Li   +4 more
openalex   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

iS2C2: a cointelligent platform for mechanistic discovery of disease cellular crosstalk

Signal Transduction and Targeted Therapy
Large language models (LLMs) have demonstrated impressive capabilities in summarization, reasoning, and content generation, yet their inability to directly interpret large-scale omics data has limited their utility in data-driven hypothesis generation ...
Jianting Sheng, Ju Young Ahn, Li Yang, Zhihao Wan, Shaohua Qi, Xiaohui Yu, Zhan Xu, Yuliang Cao, Matthew Vasquez, Amna Irfan, Yuanyuan Zhu, Hong Zhao, Zheng Yin, Ying Zhu, Yunfeng Ding, Alireza Faridar, Lin Wang, Fengshuo Liu, Hongxia Wang, Zhigang Ji, Dongxue Mao, Michael Chan, Daniel Kermany, Wenjuan Dong, Doo Yeon Kim, Xiang H.-F. Zhang, Stephen T. C. Wong   +26 more
doaj   +1 more source

A Generalized Method for Integrating Rule-based Knowledge into Inductive Methods Through Virtual Sample Creation [PDF]

, 2011
Hybrid learning methods use theoretical knowledge of a domain and a set of classified examples to develop a method for classification. Methods that use domain knowledge have been shown to perform better than inductive learners.
Iqbal, Ridwan Al
core   +1 more source

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

Proof–Based Synthesis of Sorting Algorithms Using Multisets in Theorema [PDF]

Electronic Proceedings in Theoretical Computer Science, 2019
Using multisets, we develop novel techniques for mechanizing the proofs of the synthesis conjectures for list-sorting algorithms, and we demonstrate them in the Theorema system.
Isabela Drămnesc, Tudor Jebelean
doaj   +1 more source

Status of dynamical ensemble generation

, 2010
I give an overview of current and future plans of dynamical QCD ensemble generation activities. A comparison of simulation cost between different discretizations is made. Recent developments in techniques and algorithms used in QCD dynamical simulations,
Jung, Chulwoo
core   +1 more source

Detecting Domain-Generation Algorithm (DGA) Based Fully-Qualified Domain Names (FQDNs) with Shannon Entropy [PDF]

, 2023
Adam Dorian Wong
openalex   +1 more source