Results 131 to 140 of about 259,102 (312)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Universally catenarian integral domains

Advances in Mathematics, 1988
The authors study (not necessarily Noetherian) integral domains R that have the property that the polynomial ring \(R[X_ 1,...,X_ n]\) is catenarian for each positive \(integer n\). Such domains are said to be universally catenarian. It is proved that a domain R with this property is a stably strong S-domain in the sense of \textit{S.
BOUVIER A, DOBBS DE, FONTANA, Marco
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Faster 3D finite element time domain : Floquet absorbing boundary condition modelling using recursive convolution and vector fitting [PDF]

, 2009
A recursive convolution (RC) based on the vector fitting (VF) method and triangular temporal basis functions is employed to compute the Floquet absorbing boundary condition (FABC) formulation in the vector 3D finite element time-domain (FETD) modelling ...
Cai, Yong, Mias, Christos
core   +1 more source

A time-domain integration method with equivalent complex damping model based on viscoelastic material constitutive relation

Journal of Low Frequency Noise, Vibration and Active Control
The complex damping model is only applied in frequency-domain. Based on the constitutive relation of viscoelastic materials, a vibration equation is equivalent to the constitutive relation of complex damping theory and the frequency response function ...
Jia Fan, Shuxia Wang, Panxu Sun
doaj   +1 more source

Efficient Analysis of Compact Vias in an Arbitrarily Shaped Plate Pair by Hybrid Boundary-Integral and Finite-Element Method

IEEE Access, 2019
The hybrid boundary-integral equation and finite-element method (BIE/FEM) is efficient for signal/power integrity analysis of multiple vias in a shared antipad (labeled as compact vias) in an arbitrarily shaped power/ground plate pair. According to field
Xinxin Tian, Liehui Ren, Yao-Jiang Zhang, Duo-long Wu, Gary Zhang, Dazhao Liu, Liangqi Gui   +6 more
doaj   +1 more source

Near integral domains II

Monatshefte f�r Mathematik, 1975
A direct product decomposition is given for the multiplicative semigroup of a finite near integral domain in terms of the subsemigroup of left identities and a group of automorphisms on the additive group of the domain. Conditions are given which insure that every element will have a uniquen-th root. If there existsx≠0 such that (−x)y=−(xy), for eachy,
Heatherly, H., Olivier, Horace
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Traces, extensions and co-normal derivatives for elliptic systems on Lipschitz domains [PDF]

, 2011
This is the post-print version of the article. The official published version can be accessed from the link below - Copyright @ 2011 ElsevierFor functions from the Sobolev space H^s(\Omega­), 1/2 < s < 3/2 , definitions of non-unique generalized and ...
Mikhailov, SE, Sergey E. Mikhailov, Mikhailov, Sergey E.   +2 more
core   +1 more source