Results 61 to 70 of about 331,713 (291)
Berkeley Internet Name Domain (BIND)
The Domain Name System (DNS) is a hierarchical distributed naming system for computers, services, or any resource connected to the internet or a private network. It associates several of information with domain names assigned to each of the participating
Shelena Soosay Nathan +1 more
core +1 more source
Optimization and application of the carrier DNS data analysis technology
The principles of DNS data analysis and the limitations of traditional DNS data analysis method were analyzed.According to the trend of the development of the IP network,an analysis technology based on the Hadoop towards huge amounts of DNS data was ...
Wei PENG +3 more
doaj +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Domain Name System (DNS) is one of few services on the Internet which is allowed through every security barrier. It mostly depends on the User Datagram Protocol (UDP) as the transport protocol, which is a connectionless protocol with no built-in ...
Dana Hasan +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Performance Evaluation of Multi-Cloud Failover Using Domain Name System
This research implements and analyzes a multi-cloud failover system using DNS failover via AWS Route53 and Nginx reverse proxy load balancers on Google Cloud (primary) and Herza Cloud (backup), with AWS EC2 as shared backend web servers.
Cahya Zaelani +1 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Perils of Transitive Trust in the Domain Name System [PDF]
The Domain Name System, DNS, is based on nameserver delegations, which introduce complex and subtle dependencies between names and nameservers. In this paper, we present results from a large scale survey of DNS that shows that these dependencies lead to
Emin Gün Sirer +3 more
core +2 more sources

