Results 61 to 70 of about 331,713 (291)

Berkeley Internet Name Domain (BIND)

open access: yes, 2012
The Domain Name System (DNS) is a hierarchical distributed naming system for computers, services, or any resource connected to the internet or a private network. It associates several of information with domain names assigned to each of the participating
Shelena Soosay Nathan   +1 more
core   +1 more source

Optimization and application of the carrier DNS data analysis technology

open access: yesDianxin kexue, 2018
The principles of DNS data analysis and the limitations of traditional DNS data analysis method were analyzed.According to the trend of the development of the IP network,an analysis technology based on the Hadoop towards huge amounts of DNS data was ...
Wei PENG   +3 more
doaj   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Efficient Authentication Mechanism For Defending Against Reflection-Based Attacks on Domain Name System

open access: yesKurdistan Journal of Applied Research, 2020
Domain Name System (DNS) is one of few services on the Internet which is allowed through every security barrier. It mostly depends on the User Datagram Protocol (UDP) as the transport protocol, which is a connectionless protocol with no built-in ...
Dana Hasan   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Performance Evaluation of Multi-Cloud Failover Using Domain Name System

open access: yesJournal of Applied Informatics and Computing
This research implements and analyzes a multi-cloud failover system using DNS failover via AWS Route53 and Nginx reverse proxy load balancers on Google Cloud (primary) and Herza Cloud (backup), with AWS EC2 as shared backend web servers.
Cahya Zaelani   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Perils of Transitive Trust in the Domain Name System [PDF]

open access: yes, 2005
The Domain Name System, DNS, is based on nameserver delegations, which introduce complex and subtle dependencies between names and nameservers. In this paper, we present results from a large scale survey of DNS that shows that these dependencies lead to
Emin Gün Sirer   +3 more
core   +2 more sources

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