Results 71 to 80 of about 331,713 (291)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Design and Implementation of Domain Hijacking Detection System
MATEC Web of Conferences, 2015 As the basement of Internet application, DNS plays a very critical role in the network running. On Jan. 21st, 2014, the occurrence of a serious DNS hijacking in Internet has aroused the attentions to the DNS security incident again.
Xue Jupo, Liu Yang, Chang Peng, Xiao Jun
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
, 2003 This is a multidisciplinary work that encompasses considerations of politics, regulation and technology. It considers the impact of technology on the way in which, politically, we are able to regulate technology and how we devise policy to guide that ...
Williams, Elizabeth A.
core
Perancangan Sistem Keamanan Domain Name System (DNS) Server Dengan BIND Pada PT. NOK Indonesia [PDF]
, 2010 Yolly Rinaldi , 200610225023, Perancangan Sistem Keamanan Domain Name System (DNS) Server Dengan BIND Pada PT. NOK Indonesia. Internet merupakan sarana komunikasi yang paling cepat dan murah di seluruh dunia.
Rinaldi, Yolly
core
Reachability Analysis of the Domain Name System
Proceedings of the ACM on Programming LanguagesThe high complexity of DNS poses unique challenges for ensuring its security and reliability. Despite continuous advances in DNS testing, monitoring, and verification, protocol-level defects still give rise to numerous bugs and attacks.
Dhruv Nevatia +2 more
openaire +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Out-of-court dispute resolution policy in EU electronic commerce [PDF]
The idea of common electronic market in European Union is frequent question in many aspects. From the legal point of view it is necessary to define unfair competition in this field.
Tomáš Gongol, László Áron Kóczy
core
Distributed Decentralized Domain Name Service
, 2016 We present D3NS, a system to replace the current top level DNS system and certificate authorities, offering increased scalability, security and robustness. D3NS is based on a distributed hash table and utilizes a domain name ownership system based on the
Benshoof, Brendan +7 more
core +1 more source