Results 81 to 90 of about 398,612 (306)
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Embedding domain-specific modelling languages in Maude specifications [PDF]
Software & Systems Modeling, 2011 We propose an approach for embedding Domain-Specific Modelling Languages (DSML) into Maude, based on representing models and metamodels as Maude specifications, and on representing operational semantics and model transformations as computable functions/relations between such specifications.
openaire +4 more sources
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Traffic Scenarios for Automated Vehicle Testing: A Review of Description Languages and Systems
Machines, 2021 Testing and validation of the functionalities and safety of automated vehicles shifted from a distance-based to a scenario-based method in the past decade. A number of domain-specific languages and systems were developed to support scenario-based testing.
Jing Ma +3 more
doaj +1 more source
Iterative Evaluation Of Domain-Specific Languages [PDF]
, 2013 As software moves to the daily routines and responsibilities of people, there is a need for developing tools and languages rapidly. Domain-Specific Languages (DSLs) are claimed to contribute to this productivity increase, while reducing the required maintenance and programming expertise.
openaire +3 more sources
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
A Domain-Specific Language and Simulation Architecture for the Oncilla Robot [PDF]
, 2013 Nordmann A, Tuleu A, Wrede S. A Domain-Specific Language and Simulation Architecture for the Oncilla Robot.
Wrede, Sebastian ; https://orcid.org/ +2 more
core +1 more source
A Metamodel Based Approach for UML Notated Domain Specific Modelling Language [PDF]
This paper focuses on a metamodel based approach to Unified Modelling Language (UML systems modelling and simulation. The approach allows creating a system model by operating with artefacts from the problem domain.
Krasts, Ojārs +3 more
core +2 more sources
A domain-specific language for microservices
Proceedings of the 9th ACM SIGPLAN International Symposium on Scala, 2018 A common architectural pattern for complex online systems is a collection of “microservices” communicating via RPC interfaces. A service architecture provides autonomy for teams to develop, deploy, and operate system modules without centralized coordination.
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Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source