Results 111 to 120 of about 10,126,895 (308)
Photoactive Yellow Protein (PYP) is a model system for functional protein dynamics and a prototype of the PAS domain superfamily. It is a bacterial photoreceptor that triggers a range of responses in different bacteria: phototaxis, biosynthesis of photo ...
Rosalie L. Dohmen +10 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Search for and functional annotation of multi-domain PLA2 family proteins in flatworms
The phospholipase A2 (PLA2) is a superfamily of hydrolases that catalyze the hydrolysis of phospholipids and play a key role in many molecular processes in the cells and the organism as a whole.
M. E. Bocharnikova +2 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
We have studied the influence of humidity on domain kinetics during local polarization reversal under the action of the field produced by a biased conductive tip in single-domain relaxor ferroelectric strontium barium niobate (Sr[Formula: see text]Ba ...
Vera Shikhova +5 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Accurate domain identification with structure‐anchored hidden Markov models, saHMMs
The ever increasing speed of DNA sequencing widens the discrepancy between the number of known gene products, and the knowledge of their function and structure.
Uwe H. Sauer +5 more
core +1 more source
Domain structure regularization in monocrystalline barium hexaferrite
Conditions for regular domain structure formation in a monocrystalline barium hexaferrite plate have been studied experimentally. The purpose of the work was to develop a simple and, at the same time, an effective method of regularizing the cylindrical ...
A.L. Nikytenko +3 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Misfit strain between the substrate and the superlattice plays a critical role in determining the domain configurations and ferroelectric properties of superlattice heterostructures. This implies that a proper substrate material can be selected to design
Tangrui Dan +5 more
doaj +1 more source

