Results 61 to 70 of about 10,126,895 (308)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Surface study of Tb0,16Ho0,84Fe2,00-xCox intermetallics

Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2022
The results of the study of the crystal structure, magnetic properties, as well as of micro-and domain structure of the surface of a series of compounds Tb0,16Ho0,84Fe2,00-xCox (x = 0,1; 0,2; 0,3; 0,4) are presented.
A.S. Strechen, Yu..A. Kurnosov, A.Yu.. Karpenkov, A.I. Ivanova, A.I. Sinkevich, E.M. Semenova, Yu..G. Pastushenkov   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The Synthesis and Domain Structures of Single-Crystal-Like Mesoscale BaTiO₃ Plates

Crystals, 2023
The (001) plate-like BaTiO3 piezoelectric micromaterials are synthesized by topochemical microcrystal conversion technique. BaTiO3 plates with a length of 2~10 μm and thickness of 0.5~1.3 μm are obtained.
Kun Zheng, Jian Zhuang, Yi Quan, Jinyan Zhao, Lingyan Wang, Zhe Wang, Wei Ren   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

FDO to Structure the Domain of Knowledge

Proceedings of the Conference on Research Data Infrastructure, 2023
The Globally Integrated Dataspace will evolve and result in a domain full of digital artefacts and relations which in its size and complexity is unprecedented. Traditional methods of structuring the domain such as file structures are not sufficient any longer.
Peter Wittenburg, Dimitris Koureas
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Individual globular domains and domain unfolding visualized in overstretched titin molecules with atomic force microscopy. [PDF]

, 2014
Titin is a giant elastomeric protein responsible for the generation of passive muscle force. Mechanical force unfolds titin's globular domains, but the exact structure of the overstretched titin molecule is not known.
Kellermayer Miklós, Mártonfalvi, Zsolt, Mártonfalvi Zsolt, Miklós Kellermayer, Kellermayer, Miklós, Zsolt Mártonfalvi   +5 more
core   +2 more sources

STAS Domain Structure and Function [PDF]

Cellular Physiology and Biochemistry, 2011
Pendrin shares with nearly all SLC26/SulP anion transporters a carboxy-terminal cytoplasmic segment organized around a Sulfate Transporter and Anti-Sigma factor antagonist (STAS) domain. STAS domains of divergent amino acid sequence exhibit a conserved fold of 4 β strands interspersed among 5 α helices.
Alok K, Sharma, Alan C, Rigby, Seth L, Alper   +2 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source