Results 61 to 70 of about 1,741,360 (267)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Eurasian Physical Technical Journal, 2019 The effect of inhomogeneous radially directed mechanical stresses on the domain structure of a FeBO3 single crystal is studied by a magnetooptical method.
M.Z. Sharipov +2 more
doaj +1 more source
INFLUENCE OF DEFECTS ON MAGNETIC CHARACTERISTICS OF FERRITE-GARNET FILMS
Физико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2020 This paper presents a study of the effect of volumetric (bulk) defects associated with the local mechanical damage and thermal laser action on the domain structure and magnetic characteristics of epitaxial bismuth-containing garnet-ferrite Bi:FG ...
A.I. Ivanova +5 more
doaj +1 more source
Domain structural class prediction [PDF]
Protein Engineering Design and Selection, 1998 The structural class of a protein domain can be approximately predicted according to its amino acid composition. However, can the prediction quality be improved by taking into account the coupling effect among different amino acid components? This question has evoked much controversy because completely different conclusions have been obtained by ...
K C, Chou, G M, Maggiora
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
SPONTANEOUS KINETICS OF THE DOMAIN STRUCTURE OF TRIGLYCINE SULFATE NEAR THE CURIE POINT
Конденсированные среды и межфазные границы, 2017 The kinetics of non-equilibrium stripe domain structure of ferroelectric tryglycine sulfate crystal has been studied within the temperature interval near the Curie point by the atomic force microscopy technique in the contact mode of the piezoelectric ...
Golitsyna Olga M. +3 more
doaj +1 more source
NAC Transcription Factors in Senescence: From Molecular Structure to Function in Crops
Plants, 2015 Within the last decade, NAC transcription factors have been shown to play essential roles in senescence, which is the focus of this review. Transcriptome analyses associate approximately one third of Arabidopsis NAC genes and many crop NAC genes with ...
Dagmara Podzimska-Sroka +3 more
doaj +1 more source