Results 81 to 90 of about 10,126,895 (308)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

"Effect of inhomogeneous radially directed mechanical stresses on the domain structure of a febo3 single crystal "

open access: yesEurasian Physical Technical Journal, 2019
The effect of inhomogeneous radially directed mechanical stresses on the domain structure of a FeBO3 single crystal is studied by a magnetooptical method.
M.Z. Sharipov   +2 more
doaj   +1 more source

INFLUENCE OF DEFECTS ON MAGNETIC CHARACTERISTICS OF FERRITE-GARNET FILMS

open access: yesФизико-химические аспекты изучения кластеров, наноструктур и наноматериалов, 2020
This paper presents a study of the effect of volumetric (bulk) defects associated with the local mechanical damage and thermal laser action on the domain structure and magnetic characteristics of epitaxial bismuth-containing garnet-ferrite Bi:FG ...
A.I. Ivanova   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structure of a translocation signal domain mediating conjugative transfer by Type IV secretion systems [PDF]

open access: yes, 2013
Relaxases are proteins responsible for the transfer of plasmid and chromosomal DNA from one bacterium to another during conjugation. They covalently react with a specific phosphodiester bond within DNA origin of transfer sequences, forming a nucleo ...
Redzej, Adam   +7 more
core   +1 more source

Domain structural class prediction [PDF]

open access: yesProtein Engineering Design and Selection, 1998
The structural class of a protein domain can be approximately predicted according to its amino acid composition. However, can the prediction quality be improved by taking into account the coupling effect among different amino acid components? This question has evoked much controversy because completely different conclusions have been obtained by ...
K C, Chou, G M, Maggiora
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch [PDF]

open access: yes, 2006
Riboswitches are highly structured elements in the 50-untranslated regions (50-UTRs) of messenger RNA that control gene expression by specifically binding to small metabolite molecules. They consist of an aptamer domain responsible for ligand binding and
Wöhnert, Jens   +5 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

SPONTANEOUS KINETICS OF THE DOMAIN STRUCTURE OF TRIGLYCINE SULFATE NEAR THE CURIE POINT

open access: yesКонденсированные среды и межфазные границы, 2017
The kinetics of non-equilibrium stripe domain structure of ferroelectric tryglycine sulfate crystal has been studied within the temperature interval near the Curie point by the atomic force microscopy technique in the contact mode of the piezoelectric ...
Golitsyna Olga M.   +3 more
doaj   +1 more source

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