Results 71 to 80 of about 148,500 (304)

Traitement antalgique des crises vaso-occlusives a domicile avant l´arrivee en consultation

open access: yesThe Pan African Medical Journal, 2020
INTRODUCTION: Les crises vaso-occlusives (CVO) constituent le principal motif de consultation et d’hospitalisation chez les enfants drépanocytaires et nécessite le plus souvent une prise en charge à domicile avant l’arrivée en consultation.
Alima Yanda Anastasie Nicole   +10 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Globalizing Savigny: The State in Savigny’s Private International Law, and the Challenge of Europeanization and Globalization [PDF]

open access: yes, 2005
How can conflict of laws respond to the challenges from globalization? Some argue that state-based approaches like governmental interest analysis are inadequate, and advocate a return to the approach taken by the German scholar Savigny in the 19th ...
Michaels, Ralf
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Urinary incontinence is common among people attending pulmonary rehabilitation, yet pulmonary rehabilitation has a small effect on urinary symptoms: A multicenter prospective cohort study

open access: yesPulmonology
Introduction Urinary incontinence (UI) is common among individuals with chronic respiratory diseases (CRDs) and may limit attendance, completion, and response to pulmonary rehabilitation (PR).
Francis-Edouard Gravier   +12 more
doaj   +1 more source

Company ‘Emigration’ and EC Freedom of Establishment: Daily Mail Revisited [PDF]

open access: yes, 2008
Following the ECJ’s recent case law on EC freedom of establishment (the Centros, Überseering and Inspire Art cases), regulatory competition for corporate law within the European Union takes place at an early stage of the incorporation of new companies ...
Ch Teichmann   +30 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Revue de presse club des jeunes néphrologues (CJN) : 4e trimestre 2019 de la Dialyse à Domicile

open access: yesBulletin de la Dialyse à Domicile, 2019
Introduction (NDLR) Un groupe de néphrologues issus du Club des jeunes Néphrologues sélectionne chaque mois à tour de rôle un article de la littérature internationale en rapport avec la dialyse à domicile, Dialyse Péritonéale ou Hémodialyse à Domicile,
Julie Morinière Beaume   +7 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Estimating endurance training intensity prescription from the 6-minute stepper test in people with chronic obstructive pulmonary disease – a multicenter cross-sectional study with external validation

open access: yesPulmonology
Background Home-based pulmonary rehabilitation (PR) can enhance accessibility to PR, but no at-home field exercise test has been validated for individualized endurance training prescriptions.Research question What is the accuracy of the six-minute ...
Tristan Bonnevie   +13 more
doaj   +1 more source

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