Results 71 to 80 of about 10,214 (256)

Estimating endurance training intensity prescription from the 6-minute stepper test in people with chronic obstructive pulmonary disease – a multicenter cross-sectional study with external validation

Pulmonology
Background Home-based pulmonary rehabilitation (PR) can enhance accessibility to PR, but no at-home field exercise test has been validated for individualized endurance training prescriptions.Research question What is the accuracy of the six-minute ...
Tristan Bonnevie, Augustin Clet, Marc Beaumont, Pauline Smondack, Yann Combret, Clément Médrinal, Guillaume Prieur, Fairuz Boujibar, Jean-François Muir, Antoine Cuvelier, Jean-Marie Grosbois, David Debeaumont, Elise Artaud-Macari, Francis-Edouard Gravier   +13 more
doaj   +1 more source

Revue de presse des jeunes néphrologues : 2e trimestre 2019 de la Dialyse à Domicile

Bulletin de la Dialyse à Domicile, 2019
Un groupe de néphrologues issus du Club des jeunes Néphrologues sélectionne chaque mois à tour de rôle un article de la littérature internationale en rapport avec la dialyse à domicile, Dialyse Péritonéale ou Hémodialyse à Domicile, et en propose un ...
Guillaume Seret, Laurence Vrigneaud, Stanislas Bataille, Odette Carceles, Morgane Gosselin, Antoine Lanot, Frédéric Lavainne, Julie Morinière Beaume, Céline Nodimar   +8 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Patient safety culture in home care and its related factors and outcomes: a scoping review

BMC Health Services Research
Background Patient safety culture is crucial to ensuring the quality and safety of healthcare. Assessing safety culture raises awareness of patient safety, identifies areas for improvement, and supports tracking changes over time.
Tania Martins, David Bellagamba, Michael Simon, Julie Bucher Andary, Franziska Zúñiga   +4 more
doaj   +1 more source

Domicile anglosajón y reenvío: interacción en materia de sucesiones internacionales

Revista de Derecho
Se ocupa este trabajo de analizar brevemente los conceptos de domicile of origin, domicile of choice o domicile of dependency, propios de los ordenamientos anglosajones, perfilando las líneas básicas de su complejo régimen jurídico a través del examen ...
Javier Maseda Rodríguez
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source