Results 91 to 100 of about 168 (168)

Evaluating the Intensity of Muscle Contraction by Near‐Infrared Spectroscopy, a Potential Application for Scaling Muscle Spasm

Journal of Biophotonics, EarlyView.
Near‐infrared spectroscopy (NIRS) offers a novel, non‐invasive method to assess muscle spasticity. By measuring the Tissue Oxygenation Index (TOI) during different levels of muscle contraction, this study explores the feasibility of NIRS as an objective tool for spasticity evaluation.
Mehdi Nourizadeh, Yekta Saremi, Amir Parham Pirhadi Rad, Sepideh Mortezanezhad, Iman Amani Tehrani, Jocelyn Bégin, Maria Juricic, Kishore Mulpuri, Babak Shadgan   +8 more
wiley   +1 more source

THINK Outside the Box: Integrating a DisCrit Framework With a Trauma‐Informed Care Approach to Black Disability Justice

Journal of Multicultural Counseling and Development, EarlyView.
ABSTRACT The THINK model, a Disability Critical Race Theory (DisCrit) framework and trauma‐informed care approach for working with Black Americans with disabilities in counseling, acknowledges intersections of race, disability, and historical trauma.
Aubrey D. Daniels, Crystal Victoria Socha, Troi‐Elizabeth Marshall   +2 more
wiley   +1 more source

Effect of Body Position on Dynamic Apparent Diffusion Coefficient Changes During the Cardiac Cycle in the Human Brain

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Dynamic changes in the apparent diffusion coefficient (ΔADC) during the cardiac cycle reflect water molecule fluctuations in the brain and intracranial conditions. While body position strongly affects intracranial conditions, the relationship between ΔADC and body position has been less explored, as conventional MRI is typically ...
Naoki Ohno, Tosiaki Miyati, Masatomo Uehara, Riho Okamoto, Mitsuhito Mase, Satoshi Kobayashi   +5 more
wiley   +1 more source

MR‐Guidance of Gene Therapy for Brain Diseases: Moving From Palliative Treatment to Cures

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Regulatory bodies in the U.S. and Europe recently approved a gene therapy for aromatic L‐amino acid decarboxylase (AADC) deficiency, a rare neurologic disorder where a genetic mutation prevents dopamine production in the brain. Affected children fail to develop normal motor and cognitive functions.
Dalton H. Bermudez, Thomas Lilieholm, Walter F. Block   +2 more
wiley   +1 more source

The Diagnostic Value of Contrast‐Enhanced Vessel Wall MRI for Diagnosing Neuropsychiatric Systemic Lupus Erythematosus

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Imaging biomarkers for neuropsychiatric systemic lupus erythematosus (NPSLE) are highly needed, and intracranial contrast‐enhanced vessel wall imaging (CE‐VWI) can potentially detect cerebral vessel wall abnormalities in lupus. Purpose To evaluate the diagnostic value of CE‐VWI in differentiating NPSLE from non‐NPSLE.
Satoru Ide, Yuya Fujita, Yu Murakami, Koichiro Futatsuya, Yuta Yoshimatsu, Jun Tsukamoto, Haruka Oku, Toshihiro Sakamoto, Yoshiya Tanaka, Takatoshi Aoki   +9 more
wiley   +1 more source

Repeatability of Magnetic Resonance Elastography‐Derived Mechanical Parameters in Intracranial Meningiomas

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Magnetic resonance elastography (MRE) quantifies tissue viscoelasticity, offering insights into intracranial meningiomas. MRE‐derived parameters, including the storage modulus (G') and the magnitude of the complex modulus (|G*|), may aid neurosurgical planning, but their repeatability remains unexplored in brain tumors.
Jan Saip Aunan‐Diop, Ancuta Ioana Friismose, Bo Halle, Christian Bonde Pedersen, Bo Mussmann, Emi Hojo, Ziying Yin, Mathias Just Nortvig, Kerstin Lagerstrand, Frantz Rom Poulsen   +9 more
wiley   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

Hereditary Spastic Paraplegia in Alberta: Lessons from a Well‐Defined Cohort Including the Indigenous Population

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Hereditary spastic paraplegias (HSP) are rare disorders sharing common features of leg spasticity with gait impairment. Simple and complex forms are recognized; over 50% of cases remain unsolved genetically. Little is known about the genetics of HSP among Indigenous Peoples. Objectives To describe clinical, radiological, and genetic
Ekhlas Assaedi, Setareh Ashtiani, Mehrdad A. Estiar, Ziv Gan‐Or, Erica D. McKenzie, Aakash Shetty, Guy Rouleau, Oksana Suchowersky   +7 more
wiley   +1 more source

Traditional Chinese Medicine Properties and Microcalorimetry: BioScience Evaluation

Med Research, EarlyView.
ABSTRACT The properties theory of traditional Chinese medicine (TCM), characterized by cold, hot, warm, and cool four properties, is fundamental to its development, distinguishing it from natural, botanical, and chemical medicines. However, despite its significance, there is no unified theoretical definition, bioscientific characterization, or ...
Qiang Li, Hengrui Liu, Jiayan Jin, Yixin Zhang, Shuyi Li, Lin Wang, Shirong Zhao, Chutse Wu, Zhie Fang, Jide Jin   +9 more
wiley   +1 more source

Repeat Expansions with Small TTTCA Insertions in MARCHF6 Cause Familial Myoclonus without Epilepsy

Movement Disorders, EarlyView.
Abstract Background Familial adult myoclonus epilepsy (FAME) is a rare autosomal dominant disorder caused by the same intronic TTTTA/TTTCA repeat expansion in seven distinct genes. TTTTA‐only expansions are benign, whereas those containing TTTCA insertions are pathogenic.
Theresa Kühnel, Elsa Leitão, Renate Lunzer, Fabian Kilpert, Sabine Kaya, Claudia Del Gamba, Kelly Astudillo, Steven Frucht, Marion Simonetta‐Moreau, Eric Bieth, Iris Unterberger, Giulietta Maria Riboldi, Christel Depienne   +12 more
wiley   +1 more source