Results 101 to 110 of about 168 (168)

Diffusion along Perivascular Spaces as a Marker for Glymphatic System Impairment in Huntington's Disease

Movement Disorders, EarlyView.
Abstract Background The aim was to investigate if glymphatic function is impaired in patients with Huntington's disease (HD) and its clinical relevance. Methods Forty‐nine subjects carrying mutant Huntingtin (mHTT), comprising 35 manifest (mHD) and 14 pre‐manifest (PreHD), and 35 healthy controls (HC) were recruited in this study.
Jin‐Hui Yin, Ling‐Xiao Cao, Ya‐Ou Liu, Yue Huang   +3 more
wiley   +1 more source

Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou, Prabesh Kanel, Miriam van Emde Boas, Stiven Roytman, Giulia Carli, Roger L. Albin, Nicolaas I. Bohnen   +6 more
wiley   +1 more source

Corticospinal Tract Development, Evolution, and Skilled Movements

Movement Disorders, EarlyView.
Abstract The evolution of the corticospinal tract (CST) is closely linked to the development of skilled voluntary movements in mammals. The main evolutionary divergence concerns the position of the CST within the spinal cord white matter and its postsynaptic targets in the grey matter.
Emmanuel Roze, Caroline Dubacq, Quentin Welniarz   +2 more
wiley   +1 more source

Expanding the Allelic and Clinical Heterogeneity of Movement Disorders Linked to Defects of Mitochondrial Adenosine Triphosphate Synthase

Movement Disorders, EarlyView.
Abstract Background Defects of mitochondrial ATP synthase (ATPase) represent an emerging, yet incompletely understood group of neurodevelopmental diseases with abnormal movements. Objective The aim of this study was to redefine the phenotypic and mutational spectrum of movement disorders linked to the ATPase subunit‐encoding genes ATP5F1A and ATP5F1B ...
Philip Harrer, Magdalena Krygier, Martin Krenn, Volker Kittke, Martin Danis, Georgi Krastev, Alice Saparov, Virginie Pichon, Marlène Malbos, Clarisse Scherer, Ivana Dzinovic, Matej Skorvanek, Robert Kopajtich, Holger Prokisch, Sara Silvaieh, Anna Grisold, Maria Mazurkiewicz‐Bełdzińska, Jean‐Madeleine de Sainte Agathe, Juliane Winkelmann, Jan Necpal, Robert Jech, Michael Zech   +21 more
wiley   +1 more source

Development and Preliminary Validation of a Parkinsonism‐Dystonia Scale for Infants and Young Children

Movement Disorders, EarlyView.
Abstract Background Parkinsonism in infancy is rare and is highly correlated with the presence of dystonia. Advances in treating and characterizing developmental and infantile degenerative parkinsonism have highlighted the need for a specialized assessment scale.
Roser Pons, Toni S. Pearson, Belen Perez‐Dueñas, Angels Garcia‐Cazorla, Manju A. Kurian, Zoi Dalivigka, Vasiliki Zouvelou, Chrysa Outsika, Eleftheria Kokkinou, Maria Sigatullina‐Bondarenko, Alejandra Darling, Maria del Mar O'Callaghan, Robert Spaull, Dora B.D. Steel, Evdokia Salamou, Maria João Forjaz, Carmen Rodriguez‐Blazquez   +16 more
wiley   +1 more source

Alien Limb Phenomenon and Ideomotor Apraxia as Early Indicators of Sporadic Creutzfeldt‐Jakob Disease

Movement Disorders Clinical Practice, EarlyView.
Gero Lueg, Ilka Kleffner, Markus A. Hobert   +2 more
wiley   +1 more source

Definition and Classification of Dystonia

Movement Disorders, EarlyView.
Abstract Dystonia is a movement disorder with varied clinical features and diverse etiologies. Here we present a revision of the 2013 consensus definition and classification of dystonia in light of subsequent publications and experience with its application during the last decade.
Alberto Albanese, Kailash P. Bhatia, Victor S.C. Fung, Mark Hallett, Joseph Jankovic, Christine Klein, Joachim K. Krauss, Anthony E. Lang, Jonathan W. Mink, Sanjay Pandey, Jan K. Teller, Marina A.J. Tijssen, Marie Vidailhet, H.A. Jinnah   +13 more
wiley   +1 more source

Capture of Longitudinal Change in Real‐Life Walking in Cerebellar Ataxia Increases Patient Relevance and Effect Size

Movement Disorders, EarlyView.
ABSTRACT Background With disease‐modifying drugs for degenerative ataxias on the horizon, ecologically valid measures of gait performance that can detect patient‐relevant changes in trial‐like time frames are highly warranted. Objectives In this 2‐year longitudinal study, we aimed to unravel ataxic gait measures sensitive to longitudinal changes in ...
Jens Seemann, Theresa Beyme, Natalie John, Florian Harmuth, Martin Giese, Ludger Schöls, Dagmar Timmann, Matthis Synofzik, Winfried Ilg   +8 more
wiley   +1 more source

Does Dopamine Sensitivity Influence the Choice between Subthalamotomy and Thalamotomy for Parkinsonian Tremor?

Movement Disorders, EarlyView.
Mickael Aubignat
wiley   +1 more source

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Cerebral dominance in aphasia recovery

Brain and Language, 1979
Abstract This investigation studied the patterns of ear preference of a group of 25 aphasic adults through the administration of two verbal dichotic tests and retests over a 2-month interval of time. These dichotic tests were a Dichotic Digits Test (DDT) and a Dichotic Animal Names Test (DANT).
John M. Pettit, J.Douglas Noll
openaire   +3 more sources