Results 141 to 150 of about 552,137 (300)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Different Aspects of Dominance Are Not Equivalent When Testing for Trade‐Offs in Ant Communities

Ecology and Evolution
Differences in dominance are frequently invoked to explain the outcomes of competition. Yet, what it means to be dominant, and which traits underlie dominance, are poorly understood. Here, we sought to determine the relationships between multiple aspects
Annika S. Nelson, Kailen A. Mooney
doaj   +1 more source

Color Emotion Mapping in Visual Communication Design: A Data-Driven Statistical Model Using Hue, Saturation, and Brightness

Journal of Applied Science and Engineering
Introduction: design, significantly shaping human emotions and perceptions. Understanding how different color properties influence emotional responses can improve the effectiveness and emotional impact of design.
Huang Wenqing
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Consistent Testing for Stochastic Dominance: A Subsampling Approach [PDF]

We propose a procedure for estimating the critical values of the Klecan, McFadden, and McFadden (1990) test for first and second order stochastic dominance in the general k-prospect case. Our method is based on subsampling bootstrap.
Whang, Yoon-Jae, Esfandiar Maasoumi, Oliver Linton   +2 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Stochastic Dominance, Entropy and Biodiversity Management [PDF]

In this paper we develop a model of population dynamics using the Shannon entropy index, a measure of diversity that allows for global and specific population shocks.
John C. Whitehead, Paul E. Chambers, John R. Crooker, Catherine M. Chambers   +3 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

PREFERENCE RELATIONS IN RANKING MULTIVALUED ALTERNATIVES USING STOCHASTIC DOMINANCE: CASE OF THE WARSAW STOCK EXCHANGE [PDF]

This study used stochastic dominance tests for ranking alternatives under ambiguity, to build an efficient set of assets for a different class of investors.
Grazyna Trzpiot
core