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Detecting selection-induced departures from Hardy-Weinberg proportions
Viability selection influences the genotypic contexts of alleles and leads to quantifiable departures from Hardy-Weinberg proportions. One measure of these departures is Wright's inbreeding coefficient (F), where observed heterozygosity is compared with ...
Lachance Joseph
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Dual genetic mechanisms of heterosis: population structure and gene action
IntroductionHeterosis refers to the superiority of a hybrid over its parents. Existing heterosis theory has not sufficiently addressed the contribution of inbreeding at both population level and the level of individual lines within populations.
Fernando S. Aguilar +2 more
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Genetics characteristics donor dominance short stem and large grain winter rye (Secale cereale L.)
By means of directed selection during 39 generations of Rye plants bearing the highest expression of short stem in combination with largest size of grain, a donor of dominant short stem and recessive complimentary or epistatic large size grain has been ...
В. В. Скорик +3 more
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Allele interaction--single locus genetics meets regulatory biology. [PDF]
BACKGROUND: Since the dawn of genetics, additive and dominant gene action in diploids have been defined by comparison of heterozygote and homozygote phenotypes.
Arne B Gjuvsland +3 more
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Constraining models of dominance for nonsynonymous mutations in the human genome.
Dominance is a fundamental parameter in genetics, determining the dynamics of natural selection on deleterious and beneficial mutations, the patterns of genetic variation in natural populations, and the severity of inbreeding depression in a population ...
Christopher C Kyriazis +1 more
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To date, the quantitative genetics theory for genomic selection has focused mainly on the relationship between marker and additive variances assuming one marker and one quantitative trait locus (QTL).
José Marcelo Soriano Viana +2 more
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Genomic selection models for directional dominance: an example for litter size in pigs
Background The quantitative genetics theory argues that inbreeding depression and heterosis are founded on the existence of directional dominance.
Luis Varona +3 more
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Modeling Haplotype-Haplotype Interactions in Case-Control Genetic Association Studies
Haplotype analysis has been increasingly used to study the genetic basis of human diseases, but models for characterizing genetic interactions between haplotypes from different chromosomal regions have not been well developed in the current literature ...
Li eZhang +4 more
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Population genetics and understanding of mating systems provide fundamental information for conservation planning. Pairing these methods is a powerful tool in the study of threatened species, however, they are rarely applied in concert.
Chantelle A. T. Doyle +5 more
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The impact of epistasis in the heterosis and combining ability analyses
The current theoretical knowledge concerning the influence of epistasis on heterosis is based on a simplified multiplicative model. The objective of this study was to assess how epistasis affects the heterosis and combining ability analyses, assuming ...
José Marcelo Soriano Viana
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