Results 261 to 270 of about 145,057 (324)

Dominance and recessivity in medical genetics

open access: closedThe American Journal of Medicine, 1958
Abstract 1.1. Whenever it has been possible to study the effects of abnormal human genes in double-dose, they have been found to be much more severe than the effects in single-dose. Hence these abnormal human genes are not dominant in the original sense of the word, by which it was meant that the effects of a gene in single- and double-dose were ...
A. C. Allison, Baruch S. Blumberg
openalex   +3 more sources

Mendelian inheritance revisited: dominance and recessiveness in medical genetics

open access: closedNature Reviews Genetics, 2023
Johannes Zschocke   +2 more
exaly   +2 more sources

Indirect genetics effects and evolutionary constraint: an analysis of social dominance in red deer, Cervus elaphus

open access: closedJournal of Evolutionary Biology, 2011
Mark J Adams   +2 more
exaly   +2 more sources
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Analysis of genetic dominance in the UK Biobank

Science, 2023
Classical statistical genetics theory defines dominance as any deviation from a purely additive, or dosage, effect of a genotype on a trait, which is known as the dominance deviation. Dominance is well documented in plant and animal breeding. Outside of rare monogenic traits, however, evidence in humans is limited.
Duncan S. Palmer   +11 more
openaire   +2 more sources

Genetics of the Dominant Ataxias

Seminars in Neurology, 2011
The relevant clinical, genetic, and cell biologic aspects of the dominantly inherited spinocerebellar ataxias (SCAs) are reviewed in this article. SCAs are diseases of the entire nervous system; in addition to cerebellar ataxia, the central (but not obligate) disease feature, many noncerebellar complications can be present as well.
Verbeek, D.S., Warrenburg, B.P.C. van de
openaire   +4 more sources

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