Results 121 to 130 of about 1,180,437 (249)

Angiotensin II Signaling Promotes Follicle Growth and Dominance in Cattle

, 2011
It is generally understood that angiotensin II (AngII) promotes follicle atresia in rats, although recent data suggested that this may not be true in cattle. In this study, we aimed to determine in vivo whether AngII alters follicle development in cattle,
Bernardo Gasperin, Joabel Santos, Rogério Ferreira, Monique Rovani, Paulo Bayard Dias Gonçalves, Rodrigo Bohrer, Marcos Barreta, Christopher Price   +7 more
core   +1 more source

Single‐cell RNA sequencing of peripheral blood defines two immunological subtypes of Sjögren's disease distinguished by anti‐SSA antibodies and aberrant B cell populations

Arthritis &Rheumatology, Accepted Article.
Objectives Sjögren's disease (SjD) is a heterogeneous autoimmune disorder characterized by substantial clinical and molecular diversity. This heterogeneity raises key questions regarding the existence of distinct pathogenic mechanisms underlying disease subtypes.
Geoffrey Urbanski, Kimberly E. Taylor, Emily Flynn, Armita Norouzi, Catherine Chu, Brittany Davidson, Arnab Ghosh, Joanne Nititham, Ravi K. Patel, Annie W. Poon, Gabriela K. Fragiadakis, Alexis J. Combes, Walter L. Eckalbar, Lindsey A. Criswell, Chun Jimmie Ye, Caroline H. Shiboski   +15 more
wiley   +1 more source

The effects of ovarian enzyme modulators on folliculogenesis and cyst development in the porcine ovary. [PDF]

, 2007
The first aim of the research conducted as part of this thesis was to investigate the expression and activities of 110HSD enzymes in porcine mural granulosa cells and COCs from small, medium and large antral follicles, as well as from ovarian cysts. Both
Sunak, N.
core  

Treatment‐driven peripheral blood transcriptomic remodelling and baseline predictors of ESSDAI and STAR response to B‐cell therapy in Sjögren's disease

Arthritis &Rheumatology, Accepted Article.
Objective To characterise whole‐blood transcriptomic profiles in adults with active Sjögren's disease (SjD) treated with anti‐CD20 or BlyS/BAFF inhibition, identify markers of clinical response, and define inflammatory pathways linked to non‐response. Methods Whole‐blood RNA sequencing was performed at baseline and week‐24 in participants (n=43) from a
Aimen Ibrahim, Junjie Peng, Eileen Tian, Lucia Martin‐Gutierrez, John Casement, Kyle Thompson, Wan‐Fai Ng, André van Maurik, Elizabeth C Jury, Coziana Ciurtin   +9 more
wiley   +1 more source

THE PROLIFERATION OF DOMINANT FOLLICLE CUMULUS CELLS IN IN VITRO CONDITIONS

Zdravniški Vestnik, 2002
Background. We studied the proliferative capacity of dominant follicle cumulus cells under in vitro conditions in natural in vitro fertilization (IVF) cycles.
Mojca Čižek-Sajko, Veljko Vlaisavljević   +1 more
doaj  

Seeing ourselves in anatomy: Embedding equity, diversity, and inclusivity to transform learning in a UK BSc curriculum

Anatomical Sciences Education, EarlyView.
Abstract Embedding intersectional equity, diversity, and inclusion (EDI) in anatomy education is essential to reflect the growing diversity of student populations, support all learners, and prepare graduates for a more inclusive, socially responsive global workforce.
Michelle Welsh, Ourania Varsou
wiley   +1 more source

Effects of follicle-stimulating hormone glycosylation on ovarian follicle development

, 2023
Thesis (M.S.)-- Wichita State University, College of Liberal Arts and Sciences, Dept. of Biological SciencesFollicle-stimulating hormone (FSH) is a reproductive glycoprotein hormone that exhibits macroheterogeneity in the form of absence or presence of a
Cosper, Kirsten Elisabeth
core   +1 more source

Status of oncology drugs with a conditional approval: A cross‐sectional comparison of the Food and Drug Administration and Health Canada

British Journal of Clinical Pharmacology, EarlyView.
Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley   +1 more source

Seasonal effects on follicular dynamics and hemodynamics, ovarian hormone levels, nitric oxide levels, and lactate dehydrogenase levels in native mares

Open Veterinary Journal
Background: Summer heat stress affects the regularity of the estrous cycle in different animal species. Aim: This study aimed to investigate seasonal effects on follicular dynamics, hemodynamics, and associated biomarkers across the estrous cycle in ...
Amal M. Aboelmaat, Abdalla E. A. Elgharieb, Hazem Ahmed El-Debaky, Jamal M. H. Alkhadrawy   +3 more
doaj   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source