Results 41 to 50 of about 6,180,158 (298)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

ANALYSIS OF WOMEN'S FOLLOWER’S RECEPTION IN THE YOGYAKARTA REGION ON THE TIKTOK @BASYASMAN00 ACCOUNT ABOUT RAMADHAN 1443 H EDITION OF DAKWAH CONTENT

open access: yesJurnal Da'wah, 2022
This study aims to identify and describe the reception analysis of female followers in the Yogyakarta area on the TikTok account regarding the da'wah content of the Ramadhan 1443 H edition. Research method: reception analysis.
Santa Lorita Simamora   +1 more
doaj   +1 more source

Total Positive Influence Domination on Weighted Networks [PDF]

open access: yes, 2019
We are proposing two greedy and a new linear programming based approximation algorithm for the total positive influence dominating set problem in weighted networks. Applications of this problem in weighted settings include finding: a minimum cost set of nodes to broadcast a message in social networks, such that each node has majority of neighbours ...
Danica Vukadinovic Greetham   +2 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Small Ponds in Headwater Catchments Are a Dominant Influence on Regional Nutrient and Sediment Budgets

open access: yesGeophysical Research Letters, 2019
Small ponds—farm ponds, detention ponds, or impoundments below 0.01 km2—serve important human needs throughout most large river basins. Yet the role of small ponds in regional nutrient and sediment budgets is essentially unknown, currently making it ...
N. Schmadel   +6 more
semanticscholar   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Relaciones contractuales entre las instituciones prestadoras y aseguradoras de servicios de salud del municipio de Medellín, Colombia, 2005-2006 Contractual relationships between Health Insurance Companies and hospitals, Medellín, Colombia, 2005-2006

open access: yesInvestigación y Educación en Enfermería, 2009
Objetivo: caracterizar las relaciones entre las instituciones prestadoras y las aseguradoras alrededor de los procesos de contratación. Metodología: se realizó un estudio cualitativo, en el cual se entrevistaron 29 funcionarios de diferentes ...
Zuly Andrea Rodríguez Corredor   +1 more
doaj  

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