Results 41 to 50 of about 6,180,158 (298)
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
This study aims to identify and describe the reception analysis of female followers in the Yogyakarta area on the TikTok account regarding the da'wah content of the Ramadhan 1443 H edition. Research method: reception analysis.
Santa Lorita Simamora +1 more
doaj +1 more source
Total Positive Influence Domination on Weighted Networks [PDF]
We are proposing two greedy and a new linear programming based approximation algorithm for the total positive influence dominating set problem in weighted networks. Applications of this problem in weighted settings include finding: a minimum cost set of nodes to broadcast a message in social networks, such that each node has majority of neighbours ...
Danica Vukadinovic Greetham +2 more
openaire +3 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Small ponds—farm ponds, detention ponds, or impoundments below 0.01 km2—serve important human needs throughout most large river basins. Yet the role of small ponds in regional nutrient and sediment budgets is essentially unknown, currently making it ...
N. Schmadel +6 more
semanticscholar +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Objetivo: caracterizar las relaciones entre las instituciones prestadoras y las aseguradoras alrededor de los procesos de contratación. Metodología: se realizó un estudio cualitativo, en el cual se entrevistaron 29 funcionarios de diferentes ...
Zuly Andrea Rodríguez Corredor +1 more
doaj

