Results 181 to 190 of about 1,362,273 (352)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
“Dominate”. Acrónimo de apoyo en la valoración de heridas
, 2016 El acrónimo DOMINATE favorece el abordaje integral de la lesión, dentro de la valoración general del paciente. De forma ordenada, descarta y detecta deficiencias en factores condicionantes de heridas crónicas y su consecuente control-dominio, para la ...
Crespo Villazán, Lucía +4 more
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Eagles Fall Short to CoC, Dominate UNCW and ABAC over Weekend
, 2020 Eagles Fall Short to CoC, Dominate UNCW and ABAC over ...
Georgia Southern University
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Another experimental look at reciprocal behavior: indirect reciprocity [PDF]
This paper highlights a new social motivation, the indirect reciprocity, through a three-player dictator-ultimatum game. Player 2 has the opportunity to reward or punish indirectly the player 1 by inciting – with her offer - player 3 to accept or to ...
Bonein Aurélie, Serra Daniel
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Hand Function Related to Age and Sex
Iranian Rehabilitation Journal, 2008 Objectives: The purpose of this study was for evaluation of relationship between hand function and age, sex by Jebson Taylor Test.This study determined whether age might be a factor when associated with sex.
Zohreh Sarfaraz +3 more
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The novel coronavirus and humans: who can dominate who?
Journal of Bio-X Research, 2021 Lei Cai, Lin He
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
The Doctrine of Natural Goodness: Rousseau’s Critique of the Will to Dominate in Emile [PDF]
Although Rousseau is well-known for his doctrine of the natural goodness of man, his new doctrine has not attracted much attention on how it responds to a tradition of philosophical and theological thought that centers on the related claims concerning ...
Musacchia, Miranda
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