Results 41 to 50 of about 60,217 (209)

Total domination versus paired domination [PDF]

open access: yes, 2011
A dominating set of a graph G is a vertex subset that any vertex of G either belongs to or is adjacent to. A total dominating set is a dominating set whose induced subgraph does not contain isolated vertices.
Schaudt, Oliver
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

From Gap-ETH to FPT-Inapproximability: Clique, Dominating Set, and More

open access: yes, 2017
We consider questions that arise from the intersection between the areas of polynomial-time approximation algorithms, subexponential-time algorithms, and fixed-parameter tractable algorithms.
Chalermsook, Parinya   +6 more
core   +1 more source

An O *(1.1939 n ) Time Algorithm for Minimum Weighted Dominating Induced Matching [PDF]

open access: yes, 2013
Say that an edge of a graph $G$ dominates itself and every other edge adjacent to it. An edge dominating set of a graph $G=(V,E)$ is a subset of edges $E' \subseteq E$ which dominates all edges of $G$. In particular, if every edge of $G$ is dominated by exactly one edge of $E'$ then $E'$ is a dominating induced matching.
Lin, Min Chih   +2 more
openaire   +2 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

More applications of the d-neighbor equivalence: acyclicity and connectivity constraints

open access: yes, 2018
In this paper, we design a framework to obtain efficient algorithms for several problems with a global constraint (acyclicity or connectivity) such as Connected Dominating Set, Node Weighted Steiner Tree, Maximum Induced Tree, Longest Induced Path, and ...
Bergougnoux, Benjamin   +1 more
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Local algorithms in (weakly) coloured graphs [PDF]

open access: yes, 2010
A local algorithm is a distributed algorithm that completes after a constant number of synchronous communication rounds. We present local approximation algorithms for the minimum dominating set problem and the maximum matching problem in 2-coloured and ...
Polishchuk, Valentin   +4 more
core  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Partitioning the vertex set of $G$ to make $G\,\Box\, H$ an efficient open domination graph

open access: yes, 2016
A graph is an efficient open domination graph if there exists a subset of vertices whose open neighborhoods partition its vertex set. We characterize those graphs $G$ for which the Cartesian product $G \Box H$ is an efficient open domination graph when ...
Peterin, Iztok   +3 more
core   +1 more source

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