Results 141 to 150 of about 7,194,939 (348)
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Locating-total dominating sets in twin-free graphs: a conjecture
, 2016 A total dominating set of a graph $G$ is a set $D$ of vertices of $G$ such that every vertex of $G$ has a neighbor in $D$. A locating-total dominating set of $G$ is a total dominating set $D$ of $G$ with the additional property that every two distinct ...
Foucaud, Florent, Henning, Michael A.
core
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Co-Secure Domination Number in Some Graphs
AxiomsLet G be a graph and S⊆V(G). If S is a dominating set of G, and for each vertex u∈V(G)−S, there is a neighbor of u in S, denoted by v, such that (S∖{v})∪{u} is a dominating set of G, then S is a secure dominating set (SDS) of G.
Jiatong Cui +4 more
doaj +1 more source
Extended dominating-set-based routing in ad hoc wireless networks with unidirectional links [PDF]
, 2002 Jie Wu
openalex +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
International Journal of Adaptive Control and Signal Processing, EarlyView., 2023 Summary In this contribution, we propose a detailed study of interpolation‐based data‐driven methods that are of relevance in the model reduction and also in the systems and control communities. The data are given by samples of the transfer function of the underlying (unknown) model, that is, we analyze frequency‐response data.
Quirin Aumann, Ion Victor Gosea
wiley +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
NP-completeness of weakly convex and convex dominating set decision problems [PDF]
Opuscula Mathematica, 2004 The convex domination number and the weakly convex domination number are new domination parameters. In this paper we show that the decision problems of convex and weakly convex dominating sets are \(NP\)-complete for bipartite and split graphs.
Joanna Raczek
doaj